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xylocaine dental

Xylocaine Dental (Lidocaine Hydrochloride) is an amide local anesthetic used to treat Burns, Esophageal Diseases, Mouth Diseases, Myocardial Infarction.

Lidocaine Hydrochloride · by Dentsply Pharm

Available as a generic: Lidocaine Hydrochloride Preservative Free

⚠ FDA reports a current shortage of the injection form — availability differs between suppliers — see drug shortages →
Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Pharmacy acquisition cost fell 7% — $0.2619 → $0.2434 per ml (CMS NADAC)source

Verified againstopenFDANIH DailyMedRxClass
Lower-cost optionsSave up to 74%
This medication~$0.24
Cheapest in class · exparel~$0.06
See FDA-approved alternatives

Key facts

Active ingredient
Lidocaine Hydrochloride
Form
Injectable
Strength
Lidocaine Hydrochloride 2%
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Dentsply Pharm
What the pharmacy pays
~$0.24 per ml — not your price
FDA application
NDA021380
Availability
Discontinued (per FDA)

Drug class

How this class works, per Topical, Local, and Regional Anesthesia and Anesthetics - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Xylocaine Dental ranks — best-rated amide local anesthetic for:

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Xylocaine Dental treat?
Xylocaine Dental (Lidocaine Hydrochloride) may be used to treat burns, esophageal diseases, mouth diseases, myocardial infarction, pain, paroxysmal tachycardia, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Xylocaine Dental work?
Xylocaine Dental is a amide local anesthetic. Amide local anesthetics temporarily block the sodium channels that nerves use to fire, so the treated nerves can't send signals. This numbs pain in the area, and because the block reverses as the drug wears off, sensation returns afterward.
How much does Xylocaine Dental cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.24 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Exparel — about $0.06 on the same basis.
Is there a coupon or discount for Xylocaine Dental?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Xylocaine Dental. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Xylocaine Dental?
Xylocaine Dental is marketed by Dentsply Pharm. You can see Dentsply Pharm's full profile, rating, and other products on pharmaranks.
Is Xylocaine Dental a brand-name or generic drug?
Xylocaine Dental is a brand-name product with the active ingredient Lidocaine Hydrochloride. Lower-cost generic equivalents containing Lidocaine Hydrochloride are available — ask your pharmacist.
Is Xylocaine Dental available over the counter?
No. Xylocaine Dental is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Xylocaine Dental come in?
Xylocaine Dental is currently marketed as injectable, per the FDA's National Drug Code Directory.
What class of drug is Xylocaine Dental?
Xylocaine Dental is classified as amide local anesthetic, antiarrhythmic, per the FDA's Established Pharmacologic Class.
Is Xylocaine Dental FDA-registered?
Xylocaine Dental is on record with the U.S. FDA under application number NDA021380. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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