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rayos

Rayos (Prednisone) is a corticosteroid used to treat Adrenal Insufficiency, Autoimmune Hemolytic Anemia, Asthma, Berylliosis.

Prednisone · by Horizon

Available as a generic: Prednisone

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
~$1.77 /30
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Key facts

Active ingredient
Prednisone
Drug class
Corticosteroid
Form
Tablet, delayed release
Strength
Prednisone 1MG · Prednisone 2MG · Prednisone 5MG
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Horizon
Half-life
roughly 2 to 4 hours (short) (how long it stays in your system)
What the pharmacy pays
~$1.77 for 30 — not your price
FDA application
NDA202020
Availability
Discontinued (per FDA)

How long does Prednisone stay in your body?

The elimination half-life of prednisone is roughly 2 to 4 hours (short) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Prednisone is a prodrug: the liver completely converts it to prednisolone, its active form. The FDA prednisolone label gives prednisolone a plasma elimination half-life of 2 to 4 hours, and the FDA RAYOS (prednisone) label states the terminal half-life of prednisone itself is 2 to 3 hours — so the active metabolite is NOT materially longer. Note that this blood half-life is much shorter than the drug's anti-inflammatory/biological effect, which lasts far longer (adrenal suppression persists roughly a day or more after a dose). Prednisolone is 70 to 90 percent protein-bound and cleared by the liver, so clearance can vary with liver function.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Prednisolone Sodium Phosphate Oral Solution (FDA label, DailyMed).

Drug class

How this class works, per Corticosteroids - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Rayos ranks — best-rated corticosteroid for:

Dosage forms

Tablet, delayed release

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Rayos treat?
Rayos (Prednisone) may be used to treat adrenal insufficiency, autoimmune hemolytic anemia, asthma, berylliosis, bursitis, ulcerative colitis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Rayos work?
Rayos is a corticosteroid. Corticosteroids mimic the body's natural stress hormone cortisol: they enter cells and bind a glucocorticoid receptor that switches off genes for inflammatory chemicals, calming swelling, redness, and an overactive immune response.
How much does Rayos cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $1.77 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Rayos?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Rayos. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Rayos?
Rayos is marketed by Horizon. You can see Horizon's full profile, rating, and other products on pharmaranks.
Is Rayos a brand-name or generic drug?
Rayos is a brand-name product with the active ingredient Prednisone. Lower-cost generic equivalents containing Prednisone are available — ask your pharmacist.
Is Rayos available over the counter?
No. Rayos is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Rayos come in?
Rayos is currently marketed as tablet, delayed release, per the FDA's National Drug Code Directory.
What class of drug is Rayos?
Rayos is classified as corticosteroid, per the FDA's Established Pharmacologic Class.
Is Rayos FDA-registered?
Rayos is on record with the U.S. FDA under application number NDA202020. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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