synalar
Synalar (Fluocinolone Acetonide) is a corticosteroid used to treat Atopic Dermatitis, Facial Dermatoses, Foot Dermatoses, Hand Dermatoses.
Fluocinolone Acetonide · by Eurofarma
Available as a generic: Fluocinolone Acetonide
Key facts
- Active ingredient
- Fluocinolone Acetonide
- Drug class
- Corticosteroid
- Form
- Topical
- Strength
- Fluocinolone Acetonide 0.025%
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- atopic dermatitis, facial dermatoses, foot dermatoses
- Manufacturer
- Eurofarma
- FDA application
- NDA013960
What is Synalar?
From the FDA label:Fluocinolone Acetonide Ointment USP, 0.025% is intended for topical administration. The active component is the corticosteroid fluocinolone acetonide, which has the chemical name pregna-1,4-diene-3,20-dione,6,9-difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis (oxy)]-,(6α,11β,16α)-. It has the following chemical structure: Fluocinolone Acetonide Ointment USP, 0.025% contains 0.25 mg/g of fluocinolone acetonide USP in a white petrolatum USP vehicle. Structure
How to use
Fluocinolone Acetonide Ointment is generally applied to the affected area as a thin film from two to four times daily depending on the severity of the condition. In hairy sites, the hair should be parted to allow direct contact with the lesion. Occlusive dressing may be used for the management of psoriasis or recalcitrant conditions. Some plastic films may be flammable and due care should be exercised in their use. Similarly, caution should be employed when such films are used on children or left in their proximity, to avoid the possibility of accidental suffocation. If an infection develops, the use of the occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.
Side effects
The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Hypertrichosis Maceration of the skin Itching Acneiform eruptions Secondary infection Irritation Hypopigmentation Skin atrophy Dryness Perioral dermatitis Striae Folliculitis Allergic contact dermatitis Miliaria To report SUSPECTED ADVERSE REACTIONS, contact ANI Pharmaceuticals, Inc. at 1-855-204-1431 or FDA at 1-800-FDA-1088 or www.fda/gov/medwatch.
Who should not take Synalar
Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Overdose — what happens if you take too much
Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects (see PRECAUTIONS ) .
U.S. Poison Control: call or text 1-800-222-1222 (free, 24/7). In an emergency call 911. From the FDA label; not medical advice.
Drug class
How this class works, per Corticosteroids - StatPearls - NCBI Bookshelf.
May treat (source: NIH RxClass)
See how Synalar ranks — best-rated corticosteroid for:
Dosage forms
Topical
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
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Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
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Frequently asked questions
- What does Synalar treat?
- Synalar (Fluocinolone Acetonide) may be used to treat atopic dermatitis, facial dermatoses, foot dermatoses, hand dermatoses, inflammation, leg dermatoses, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Synalar work?
- Synalar is a corticosteroid. Corticosteroids mimic the body's natural stress hormone cortisol: they enter cells and bind a glucocorticoid receptor that switches off genes for inflammatory chemicals, calming swelling, redness, and an overactive immune response.
- Is there a coupon or discount for Synalar?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Synalar. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Synalar?
- Synalar is marketed by Eurofarma. You can see Eurofarma's full profile, rating, and other products on pharmaranks.
- Is Synalar a brand-name or generic drug?
- Synalar is a brand-name product with the active ingredient Fluocinolone Acetonide. Lower-cost generic equivalents containing Fluocinolone Acetonide are available — ask your pharmacist.
- Is Synalar available over the counter?
- No. Synalar is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Synalar come in?
- Synalar is currently marketed as topical, per the FDA's National Drug Code Directory.
- What class of drug is Synalar?
- Synalar is classified as corticosteroid, per the FDA's Established Pharmacologic Class.
- Is Synalar FDA-registered?
- Synalar is on record with the U.S. FDA under application number NDA013960. You can verify this on its official FDA label.
- Is Synalar safe?
- There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Synalar. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
- What are the side effects of Synalar?
- Synalar's side effects are taken directly from its FDA label. From the label: The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings.… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.
Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about FLUOCINOLONE ACETONIDE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 1,990 reports naming FLUOCINOLONE ACETONIDE — the active ingredient in Synalar, and the FDA flagged 43% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- pruritus177 reports
- rash153 reports
- diarrhoea124 reports
- headache117 reports
- psoriasis107 reports
- nausea103 reports
- fatigue99 reports
- dermatitis atopic83 reports
Read these as a signal, not a rate. A report does not mean FLUOCINOLONE ACETONIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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