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megace

Pharmaranks rates Megace 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Megace (Megestrol Acetate) is a progestin used to treat Anorexia, Breast Neoplasms, Cachexia, Endometrial Neoplasms.

Megestrol Acetate · by Bristol Myers Squibb

Available as a generic: Megestrol Acetate

72/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Megestrol Acetate
Drug class
Progestin
Form
Tablet, Suspension
Strength
Megestrol Acetate 40MG/ML **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
What the pharmacy pays
~$7.14 for 30 — not your price
FDA application
NDA020264
Availability
Discontinued (per FDA)

Drug class

How this class works, per Progestins - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Megace ranks — best-rated progestin for:

Dosage forms

Tablet and Suspension

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Megace treat?
Megace (Megestrol Acetate) may be used to treat anorexia, breast neoplasms, cachexia, endometrial neoplasms, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Megace work?
Megace is a progestin. Progestins are lab-made versions of the hormone progesterone. Acting through progesterone receptors, they quiet the brain signals that trigger ovulation, thicken cervical mucus so sperm cannot pass, and thin the uterine lining, which together help prevent pregnancy and regulate periods.
How is Megace rated?
pharmaranks gives Megace a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Megace cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $7.14 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Megace?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Megace. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Megace?
Megace is marketed by Bristol Myers Squibb. You can see Bristol Myers Squibb's full profile, rating, and other products on pharmaranks.
Is Megace a brand-name or generic drug?
Megace is a brand-name product with the active ingredient Megestrol Acetate. Lower-cost generic equivalents containing Megestrol Acetate are available — ask your pharmacist.
Is Megace available over the counter?
No. Megace is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Megace come in?
Megace is currently marketed as tablet and suspension, per the FDA's National Drug Code Directory.
What class of drug is Megace?
Megace is classified as progestin, per the FDA's Established Pharmacologic Class.
Is Megace FDA-registered?
Megace is on record with the U.S. FDA under application number NDA020264. You can verify this on its official FDA label.
Has Megace been recalled by the FDA?
Megace has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Megace safe?
There's no single safe-or-not verdict. pharmaranks gives Megace a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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