lodine xl

How long does Etodolac stay in your body?

The elimination half-life of etodolac is about 6.4 hours (roughly 6 to 8 hours; label reports a mean terminal half-life of 6.4 hours with 22% coefficient of variation) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal (elimination) half-life, distinct from any distribution phase. Etodolac is a racemic NSAID; the [+]S-enantiomer is the active form, and there is no active metabolite that outlasts the parent (the main metabolites are inactive hydroxylated forms and etodolac glucuronide) — so the parent half-life is the relevant one, and it is not a prodrug. Population effects per the label: essentially unchanged in older adults (mean 6.5 h) and no dose adjustment recommended by age alone; modestly longer in females (mean 7.9 h); in hepatic impairment the terminal half-life was similar (mean 5.7 h); in renal impairment / hemodialysis it ranged about 5.1 to 7.5 h and dose adjustment is not generally necessary. Note the label reports total etodolac pharmacokinetics — free (unbound) drug clearance can rise in these populations even when total half-life looks stable. Not a drug-test detection window and not dosing guidance.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Etodolac tablet — DailyMed label, Clinical Pharmacology / Pharmacokinetics.

Frequently asked questions

What does Lodine XL treat?

Lodine XL (Etodolac) may be used to treat rheumatoid arthritis, osteoarthritis, pain, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How does Lodine XL work?

Lodine XL is a nonsteroidal anti-inflammatory drug. NSAIDs block cyclooxygenase (COX) enzymes that your body uses to make prostaglandins, the chemicals behind pain, swelling, and fever. Lowering prostaglandins eases pain and inflammation and brings down a high temperature.

How much does Lodine XL cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $22.58 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Lodine XL?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Lodine XL. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Lodine XL?

Lodine XL is marketed by Wyeth Pharms Inc. You can see Wyeth Pharms Inc's full profile, rating, and other products on pharmaranks.

Is Lodine XL a brand-name or generic drug?

Lodine XL is a brand-name product with the active ingredient Etodolac. Lower-cost generic equivalents containing Etodolac are available — ask your pharmacist.

Is Lodine XL available over the counter?

No. Lodine XL is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Lodine XL come in?

Lodine XL is currently marketed as tablet, extended release, per the FDA's National Drug Code Directory.

What class of drug is Lodine XL?

Lodine XL is classified as nonsteroidal anti-inflammatory drug, per the FDA's Established Pharmacologic Class.

Is Lodine XL FDA-registered?

Lodine XL is on record with the U.S. FDA under application number NDA020584. You can verify this on its official FDA label.