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lexette

Pharmaranks rates Lexette 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Lexette (Halobetasol Propionate) is a corticosteroid used to treat Facial Dermatoses, Foot Dermatoses, Hand Dermatoses, Inflammation.

Halobetasol Propionate · by Mayne Pharma

Available as a generic: Halobetasol Propionate

72/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate
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Key facts

Active ingredient
Halobetasol Propionate
Drug class
Corticosteroid
Form
Spray/Inhaler, Topical
Strength
Halobetasol Propionate 0.05%
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Mayne Pharma
FDA application
NDA210566
Availability
Discontinued (per FDA)

Drug class

How this class works, per Corticosteroids - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Lexette ranks — best-rated corticosteroid for:

Dosage forms

Spray/Inhaler and Topical

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Lexette treat?
Lexette (Halobetasol Propionate) may be used to treat facial dermatoses, foot dermatoses, hand dermatoses, inflammation, leg dermatoses, pruritus, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Lexette work?
Lexette is a corticosteroid. Corticosteroids mimic the body's natural stress hormone cortisol: they enter cells and bind a glucocorticoid receptor that switches off genes for inflammatory chemicals, calming swelling, redness, and an overactive immune response.
How is Lexette rated?
pharmaranks gives Lexette a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Lexette?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Lexette. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Lexette?
Lexette is marketed by Mayne Pharma. You can see Mayne Pharma's full profile, rating, and other products on pharmaranks.
Is Lexette a brand-name or generic drug?
Lexette is a brand-name product with the active ingredient Halobetasol Propionate. Lower-cost generic equivalents containing Halobetasol Propionate are available — ask your pharmacist.
Is Lexette available over the counter?
No. Lexette is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Lexette come in?
Lexette is currently marketed as spray/inhaler and topical, per the FDA's National Drug Code Directory.
What class of drug is Lexette?
Lexette is classified as corticosteroid, per the FDA's Established Pharmacologic Class.
Is Lexette FDA-registered?
Lexette is on record with the U.S. FDA under application number NDA210566. You can verify this on its official FDA label.
Has Lexette been recalled by the FDA?
Lexette has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Lexette safe?
There's no single safe-or-not verdict. pharmaranks gives Lexette a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about HALOBETASOL PROPIONATE

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 893 reports naming HALOBETASOL PROPIONATE — the active ingredient in Lexette, and the FDA flagged 30% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • psoriasis132 reports
  • pruritus84 reports
  • rash61 reports
  • dry skin49 reports
  • arthralgia48 reports
  • dermatitis atopic43 reports
  • skin exfoliation43 reports
  • fatigue36 reports

Read these as a signal, not a rate. A report does not mean HALOBETASOL PROPIONATE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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