omnipred
Pharmaranks rates Omnipred 3.2/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Omnipred (Prednisolone Acetate) is a corticosteroid used to treat Adrenal Insufficiency, Hemolytic Anemia, Asthma, Berylliosis.
Prednisolone Acetate · by Sandoz
Available as a generic: Prednisolone Acetate
Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →
Key facts
- Active ingredient
- Prednisolone Acetate
- Drug class
- Corticosteroid
- Form
- Drops
- Strength
- Prednisolone Acetate 1%
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- adrenal insufficiency, hemolytic anemia, asthma
- Manufacturer
- Sandoz
- Half-life
- 2 to 4 hours (how long it stays in your system)
- What the pharmacy pays
- ~$0.60 per ml — not your price
- FDA application
- NDA017469
What is Omnipred?
From the FDA label:Prednisolone acetate ophthalmic suspension is an adrenocortical steroid product prepared as sterile ophthalmic suspension for topical ophthalmic use. The active ingredient is represented by the chemical structure: Established name: Prednisolone Acetate Chemical name: Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-,(11β)-. Each mL contains: Active : prednisolone acetate 1.0%. Preservative : benzalkonium chloride 0.01%. Inactives: citric acid monohydrate (to adjust pH), dibasic sodium phosphate, edetate disodium, glycerin, hypromellose, polysorbate 80, purified water, sodium hydroxide (to adjust pH). chemical
How to use
Two drops topically in the affected eye(s) four times daily. In cases of bacterial infections, concomitant use of anti-infective agents is mandatory. Care should be taken not to discontinue therapy prematurely. If signs and symptoms fail to improve after two days, the patient should be reevaluated (see PRECAUTIONS ). The dosing of prednisolone acetate ophthalmic suspension may be reduced, but care should be taken not to discontinue therapy prematurely. In chronic conditions, withdrawal of treatment should be carried out by gradually decreasing the frequency of applications.
Side effects
Adverse reactions include, in decreasing order of frequency, elevation of IOP with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing. Although systemic effects are extremely uncommon, there have been rare occurrences of systemic hypercorticoidism after use of topical steroids. Corticosteroid-containing preparations have also been reported to cause acute anterior uveitis and perforation of the globe. Keratitis, conjunctivitis, corneal ulcers, mydriasis, conjunctival hyperemia, loss of accommodation and ptosis have occasionally been reported following local use of corticosteroids. The development of secondary ocular infection (bacterial, fungal and viral) has occurred. Fungal and viral infections of the cornea are particularly prone to develop coincidentally with long-term applications of steroid. The possibility of fungal invasion should be considered in any persistent corneal ulceration where steroid treatment has been used (see WARNINGS ). The following additional adverse reactions have been reported with prednisolone use: Cushing’s syndrome and adrenal suppression may occur after very frequent use of ophthalmic prednisolone, particularly in very young children.
Warnings
Important safety information
Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision, and in posterior subcapsular cataract formation. Prolonged use may also suppress the host immune response and thus increase the hazard of secondary ocular infections. Various ocular diseases and long-term use of topical corticosteroids have been known to cause corneal and scleral thinning. Use of topical corticosteroids in the presence of thin corneal or scleral tissue may lead to perforation. Acute purulent infections of the eye may be masked or activity enhanced by the presence of corticosteroid medication. If this product is used for 10 days or longer, intraocular pressure (IOP) should be routinely monitored even though it may be difficult in children and uncooperative patients. Steroids should be used with caution in the presence of glaucoma. IOP should be checked frequently. The use of steroids after cataract surgery may delay healing and increase the incidence of bleb formation. Use of ocular steroids may prolong the course and may exacerbate the severity of many viral infections of the eye (including herpes simplex). Employment of a corticosteroid medication in the treatment of patients with a history of herpes simplex requires great caution; frequent slit lamp microscopy is recommended. Corticosteroids are not effective in mustard gas keratitis and Sjogren's keratoconjunctivitis.
Who should not take Omnipred
Prednisolone acetate ophthalmic suspension is contraindicated in most viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures. Prednisolone acetate ophthalmic suspension is also contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids.
How long does Prednisolone Acetate stay in your body?
The elimination half-life of prednisolone acetate is 2 to 4 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma (elimination) half-life; the label states prednisolone "is eliminated from the plasma with a half-life of 2 to 4 hours" and is 70-90% protein bound. Prednisolone is itself the active corticosteroid (prednisone is the prodrug that is converted to prednisolone in the liver), so no active metabolite outlasts it. Its biological/anti-inflammatory effect lasts much longer than the plasma half-life — prednisolone is an intermediate-acting glucocorticoid with a tissue effect of roughly 18-36 hours, which is why once-daily dosing works. It is metabolized mainly in the liver, so clearance can be slowed and the half-life prolonged in significant liver impairment. Note that the plasma half-life is not the same as a drug-test detection window.
This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: PediaPred (prednisolone sodium phosphate) oral solution — FDA label via DailyMed.
Drug class
How this class works, per Corticosteroids - StatPearls - NCBI Bookshelf.
May treat (source: NIH RxClass)
See how Omnipred ranks — best-rated corticosteroid for:
Dosage forms
Drops
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Omnipred treat?
- Omnipred (Prednisolone Acetate) may be used to treat adrenal insufficiency, hemolytic anemia, asthma, berylliosis, brain neoplasms, ulcerative colitis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Omnipred work?
- Omnipred is a corticosteroid. Corticosteroids mimic the body's natural stress hormone cortisol: they enter cells and bind a glucocorticoid receptor that switches off genes for inflammatory chemicals, calming swelling, redness, and an overactive immune response.
- How is Omnipred rated?
- pharmaranks gives Omnipred a composite score of 3.2 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
- How much does Omnipred cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.60 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
- Is there a coupon or discount for Omnipred?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Omnipred. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Omnipred?
- Omnipred is marketed by Sandoz. You can see Sandoz's full profile, rating, and other products on pharmaranks.
- Is Omnipred a brand-name or generic drug?
- Omnipred is a brand-name product with the active ingredient Prednisolone Acetate. Lower-cost generic equivalents containing Prednisolone Acetate are available — ask your pharmacist.
- Is Omnipred available over the counter?
- No. Omnipred is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Omnipred come in?
- Omnipred is currently marketed as drops, per the FDA's National Drug Code Directory.
- What class of drug is Omnipred?
- Omnipred is classified as corticosteroid, per the FDA's Established Pharmacologic Class.
- Is Omnipred FDA-registered?
- Omnipred is on record with the U.S. FDA under application number NDA017469. You can verify this on its official FDA label.
- Has Omnipred been recalled by the FDA?
- Yes. Omnipred has 1 recorded FDA recall event in the openFDA enforcement database. A recall removes specific lots from the market — usually for manufacturing, contamination, potency, or labeling issues — and does not mean the drug is unsafe to take; your specific lot was almost certainly never affected. This recall history is factored into its safety score above. Always check the FDA recall database or your pharmacist for current alerts.
- Is Omnipred safe?
- There's no single safe-or-not verdict. pharmaranks gives Omnipred a recall-safety score of 64/100, based on its FDA recall history (1 recorded recall event) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.
- What are the side effects of Omnipred?
- Omnipred's side effects are taken directly from its FDA label. From the label: Adverse reactions include, in decreasing order of frequency, elevation of IOP with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing. Although systemic effects are extremely uncommon,… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.
Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about PREDNISOLONE ACETATE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 197,022 reports naming PREDNISOLONE ACETATE — the active ingredient in Omnipred, and the FDA flagged 93% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- pyrexia9,124 reports
- dyspnoea7,608 reports
- pneumonia7,481 reports
- diarrhoea7,330 reports
- nausea6,101 reports
- fatigue5,708 reports
- vomiting5,646 reports
- headache5,236 reports
Read these as a signal, not a rate. A report does not mean PREDNISOLONE ACETATE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 26, 2026.
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omnipred
64/100