declomycin
Declomycin (Demeclocycline Hydrochloride) is a tetracycline-class antimicrobial used to treat Acne Vulgaris, Actinomycosis, Campylobacter Infections, Cholera.
Demeclocycline Hydrochloride · by Lederle
Key facts
- Active ingredient
- Demeclocycline Hydrochloride
- Drug class
- Tetracycline-Class Antimicrobial
- Form
- Tablet
- Strength
- Demeclocycline Hydrochloride 150MG
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- acne vulgaris, actinomycosis, campylobacter infections
- Manufacturer
- Lederle
- What the pharmacy pays
- ~$97.72 for 30 — not your price
- FDA application
- NDA050262
- Availability
- Discontinued (per FDA)
Foods & drinks to be careful with
Well-established interactions for this medicine’s drug class, summarized from public health authorities. General information, not medical advice — always confirm with your pharmacist or the label.
Dairy, calcium, iron & antacids
Watch out for: milk and other dairy, calcium- or iron-fortified foods and supplements, and antacids.
Calcium, magnesium, and iron bind to these antibiotics in the gut and can stop them from being absorbed, making the medicine work less well.
What to do: Separate the antibiotic from dairy, supplements, and antacids by a couple of hours — take it at the interval the label or your pharmacist specifies.
Source: Tetracycline — MedlinePlus (U.S. National Library of Medicine) · Ciprofloxacin (a fluoroquinolone) — MedlinePlus (U.S. National Library of Medicine)
Drug class
May treat (source: NIH RxClass)
Dosage forms
Tablet
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Declomycin treat?
- Declomycin (Demeclocycline Hydrochloride) may be used to treat acne vulgaris, actinomycosis, campylobacter infections, cholera, clostridium infections, gonorrhea, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How much does Declomycin cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $97.72 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
- Is there a coupon or discount for Declomycin?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Declomycin. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Declomycin?
- Declomycin is marketed by Lederle. You can see Lederle's full profile, rating, and other products on pharmaranks.
- Is Declomycin a brand-name or generic drug?
- Declomycin is a brand-name product with the active ingredient Demeclocycline Hydrochloride.
- Is Declomycin available over the counter?
- No. Declomycin is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Declomycin come in?
- Declomycin is currently marketed as tablet, per the FDA's National Drug Code Directory.
- What class of drug is Declomycin?
- Declomycin is classified as tetracycline-class antimicrobial, per the FDA's Established Pharmacologic Class.
- Is Declomycin FDA-registered?
- Declomycin is on record with the U.S. FDA under application number NDA050262. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about DEMECLOCYCLINE HYDROCHLORIDE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 38 reports naming DEMECLOCYCLINE HYDROCHLORIDE — the active ingredient in Declomycin, and the FDA flagged 71% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- hyponatraemia6 reports
- stevens-johnson syndrome3 reports
- abdominal pain2 reports
- acute kidney injury2 reports
- diabetes insipidus2 reports
- diarrhoea2 reports
- hypernatraemia2 reports
- hypersensitivity2 reports
Read these as a signal, not a rate. A report does not mean DEMECLOCYCLINE HYDROCHLORIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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