Demeclocycline: uses, dosing, side effects & brands
Demeclocycline is a medicine sold in the U.S. under one brand. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Tablet
- Sold as
- Declomycin
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
- What the pharmacy pays
- about $104 for a 30-count supply — not your price
Every demeclocycline product we track (1)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
Only one: Declomycin.
What demeclocycline pills look like
Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.
How long demeclocycline keeps
No demeclocycline label we read sets a separate limit for after opening, but they do specify how it must be stored — and the stability behind any date assumes those conditions.
Does demeclocycline expire? The in-use limits and storage rules from its labelsDemeclocycline and breastfeeding
From LactMed, the US National Library of Medicine’s Drugs and Lactation Database — quoted, not rewritten.
Full LactMed record for demeclocycline: levels in milk, effects in breastfed infants, and the drugs it would consider insteadA number of reviews have stated that tetracyclines are contraindicated during breastfeeding because of possible staining of infants’ dental enamel or bone deposition. However, available literature indicates that there is not likely to be harm in short-term use of demeclocycline during lactation because milk levels are low and absorption by the infant is inhibited by the calcium in breastmilk. Although the manufacturer recommends avoiding breastfeeding during administration of demeclocycline, short-term use of demeclocycline is probably acceptable in nursing mothers. As a theoretical precaution, avoid prolonged or repeat courses during nursing. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash).
National Institute of Child Health and Human Development, record revised June 15, 2025. LactMed states its information is not a substitute for professional judgement.
What people report to the FDA about demeclocycline
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 38 reports naming demeclocycline, and the FDA flagged 71% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- hyponatraemia6 reports
- stevens-johnson syndrome3 reports
- abdominal pain2 reports
- acute kidney injury2 reports
- diabetes insipidus2 reports
- diarrhoea2 reports
- hypernatraemia2 reports
- hypersensitivity2 reports
Read these as a signal, not a rate. A report does not mean demeclocycline caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.
Source: openFDA drug/event (FAERS), retrieved July 25, 2026.
Related calculators
Frequently asked questions
Can you take demeclocycline with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run demeclocycline against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What forms does demeclocycline come in?
Across the brands we track, demeclocycline is currently marketed as tablet, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic demeclocycline?
We do not currently list a generic-labelled demeclocycline product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Demeclocycline: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/demeclocycline
- MLA
- “Demeclocycline: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/demeclocycline.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for demeclocycline on DailyMed (NIH) ↗.