DECLOMYCIN vs DORYX MPC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. DECLOMYCIN and DORYX MPC are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DECLOMYCIN	DORYX MPC
Rating	New	70/100
Pharmacy pays	~$103.92 /30	$0.12 /mL
Type	RX	RX
Active ingredient	DEMECLOCYCLINE HYDROCHLORIDE	DOXYCYCLINE HYCLATE
Manufacturer	Lederle	Mayne Pharma
Dosage forms	Tablet	Tablet, delayed release
Drug class	Tetracycline-Class Antimicrobial	Tetracycline-Class Drug
Boxed warning	None	None
Half-life	—	about 16 to 22 hours in healthy adults
Treats	Acne Vulgaris, Actinomycosis, Campylobacter Infections	Anthrax, Campylobacter Infections, Cholera

declomycin doryx mpc

Rating

New

70/100

Pharmacy pays

~$103.92 /30

$0.12 /mL

Type

Active ingredient

DEMECLOCYCLINE HYDROCHLORIDE

DOXYCYCLINE HYCLATE

Manufacturer

Lederle

Mayne Pharma

Dosage forms

Tablet

Tablet, delayed release

Drug class

Tetracycline-Class Antimicrobial

Tetracycline-Class Drug

Boxed warning

None

Half-life

—

about 16 to 22 hours in healthy adults

Treats

Acne Vulgaris, Actinomycosis, Campylobacter Infections

Anthrax, Campylobacter Infections, Cholera

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Frequently asked questions

What is the difference between Declomycin and Doryx Mpc?

Declomycin contains Demeclocycline Hydrochloride, while Doryx Mpc contains Doxycycline Hyclate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.