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Best treatments for clostridium infections

6 products may treat clostridium infections, spanning FDA drug classes such as cephalosporin antibacterial. The current highest-rated option is cefotan. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 6 drugs we list for clostridium infections, 2 are available as lower-cost generics, spanning classes such as cephalosporin antibacterial. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for clostridium infections — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Top-rated picks for clostridium infections: 1. Cefotan · 2. Zinplava · 3. Cefoxitin

Top-rated treatments for clostridium infections, ranked by pharmaranks score
#DrugRatingPharmacy pays
170/100View →
270/100View →
3Not yet ratedView →
4Not yet rated$43View →
5Not yet rated$43View →
6Not yet ratedView →

Full ranking · 6 treatments

PAI HOLDINGS PHARM logo
#3 of 19 in Cephalosporin Antibacterial

cefotan

PrescriptionFDA-sourced

70/100

Cefotan (Cefotetan Disodium) is a cephalosporin antibacterial used to treat Abscess, Bacteroides Infections, Human Bites, Infectious Bone Diseases.

(2 data points)
cephalosporin antibacterialabscessbacteroides infections

Price varies

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MERCK SHARP DOHME logo

zinplava

PrescriptionFDA-sourced

70/100

Zinplava (Bezlotoxumab) is a medication used to treat Clostridium Infections.

(3 data points)
clostridium infections

Price varies

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cefoxitin

PrescriptionFDA-sourced

New

Cefoxitin (Cefoxitin Sodium) is a cephalosporin antibacterial used to treat Abscess, Bacteroides Infections, Infectious Bone Diseases, Clostridium Infections.

cephalosporin antibacterialabscessbacteroides infections

Price varies

View details →

ceftriaxone

PrescriptionFDA-sourced

New

Ceftriaxone (Ceftriaxone Sodium) is a cephalosporin antibacterial used to treat Acinetobacter Infections, Infectious Bone Diseases, Chancroid, Clostridium Infections.

cephalosporin antibacterialacinetobacter infectionsbone diseases, infectious

Pharmacy pays

From ~$25.87/30· 4 forms Save up to 79% in class
View details →

ceftriaxone and dextrose in duplex container

PrescriptionFDA-sourced

New

Ceftriaxone and Dextrose in Duplex Container (Ceftriaxone Sodium) is a cephalosporin antibacterial used to treat Acinetobacter Infections, Infectious Bone Diseases, Chancroid, Clostridium Infections.

cephalosporin antibacterialacinetobacter infectionsbone diseases, infectious

Pharmacy pays

From ~$25.87/30· 4 forms Save up to 79% in class
View details →

tygacil

Boxed warning

PrescriptionFDA-sourced

New

Tygacil (Tigecycline) is a medication used to treat Bacteroides Infections, Clostridium Infections, Escherichia Coli Infections, Haemophilus Infections.

bacteroides infectionsclostridium infectionsescherichia coli infections

Price varies

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Frequently asked

What treats clostridium infections?
Our catalog lists 6 products that may treat clostridium infections, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is cefotan.
What is the best-rated treatment for clostridium infections?
By our independent recall-safety rating — not an efficacy measure — cefotan ranks highest among the products we list for clostridium infections. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat clostridium infections?
Treatments for clostridium infections span FDA drug classes including cephalosporin antibacterial. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.