Skip to content
ppharmaranks
Menu

Best Cephalosporin Antibacterial for clostridium infections

Top-rated pick: Cefotan — pharmaranks score 70/100, the highest of the 5 Cephalosporin Antibacterial drugs used for clostridium infections, ranked by our independent FDA recall-safety score. Compare them with all treatments for clostridium infections or the full Cephalosporin Antibacterial class. Not medical advice — always consult a professional.

Quick answer: Of the 5 cephalosporin antibacterial drugs we rate for clostridium infections, 2 are available as lower-cost generics, and most are injectable. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for clostridium infections; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

How cephalosporin antibacterial work

Cephalosporins kill bacteria by blocking the proteins they use to build their cell walls. Without an intact wall, the bacterium cannot hold its shape and dies, which clears the infection.

Source: Cephalosporins - StatPearls - NCBI Bookshelf

Top cephalosporin antibacterial for clostridium infections: 1. Cefotan · 2. Cefoxitin · 3. Cefoxitin in Plastic Container

Best-rated Cephalosporin Antibacterial for clostridium infections, ranked by pharmaranks score
#DrugRatingPharmacy pays
170/100View →
2Not yet ratedView →
3Not yet ratedView →
4Not yet rated$43View →
5Not yet rated$43View →

Full ranking · 5 drugs

PAI HOLDINGS PHARM logo
#3 of 19 in Cephalosporin Antibacterial

cefotan

PrescriptionFDA-sourced

70/100

Cefotan (Cefotetan Disodium) is a cephalosporin antibacterial used to treat Abscess, Bacteroides Infections, Human Bites, Infectious Bone Diseases.

(2 data points)
cephalosporin antibacterialabscessbacteroides infections

Price varies

View details →

cefoxitin

PrescriptionFDA-sourced

New

Cefoxitin (Cefoxitin Sodium) is a cephalosporin antibacterial used to treat Abscess, Bacteroides Infections, Infectious Bone Diseases, Clostridium Infections.

cephalosporin antibacterialabscessbacteroides infections

Price varies

View details →

cefoxitin in plastic container

Boxed warning

PrescriptionFDA-sourced

New

Cefoxitin in Plastic Container (Cefoxitin Sodium) is a cephalosporin antibacterial used to treat Abscess, Bacteroides Infections, Infectious Bone Diseases, Clostridium Infections.

cephalosporin antibacterialabscessbacteroides infections

Price varies

View details →

ceftriaxone

PrescriptionFDA-sourced

New

Ceftriaxone (Ceftriaxone Sodium) is a cephalosporin antibacterial used to treat Acinetobacter Infections, Infectious Bone Diseases, Chancroid, Clostridium Infections.

cephalosporin antibacterialacinetobacter infectionsbone diseases, infectious

Pharmacy pays

From ~$25.87/30· 4 forms Save up to 79% in class
View details →

ceftriaxone and dextrose in duplex container

PrescriptionFDA-sourced

New

Ceftriaxone and Dextrose in Duplex Container (Ceftriaxone Sodium) is a cephalosporin antibacterial used to treat Acinetobacter Infections, Infectious Bone Diseases, Chancroid, Clostridium Infections.

cephalosporin antibacterialacinetobacter infectionsbone diseases, infectious

Pharmacy pays

From ~$25.87/30· 4 forms Save up to 79% in class
View details →

Frequently asked

What is the best cephalosporin antibacterial for clostridium infections?
By our independent recall-safety rating — not an efficacy measure — cefotan ranks highest among Cephalosporin Antibacterial drugs used for clostridium infections. Always consult a professional.
Which cephalosporin antibacterial drugs treat clostridium infections?
pharmaranks lists 5 Cephalosporin Antibacterial products used for clostridium infections, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.