cefoxitin in plastic container
Cefoxitin in Plastic Container (Cefoxitin Sodium) is a cephalosporin antibacterial used to treat Abscess, Bacteroides Infections, Infectious Bone Diseases, Clostridium Infections.
Cefoxitin Sodium · by Samson Medcl
Generic of Mefoxin in Dextrose 5% in Plastic Container
Key facts
- Active ingredient
- Cefoxitin Sodium
- Drug class
- Cephalosporin Antibacterial
- Form
- Injectable
- Strength
- Cefoxitin Sodium EQ 100GM Base
- Type
- Prescription (Rx)
- Brand or generic
- Generic
- Manufacturer
- Samson Medcl
- FDA application
- ANDA200938
- FDA boxed warning
- Yes — see the boxed warning
What is Cefoxitin in Plastic Container?
From the FDA label:Cefoxitin for Injection, USP, Pharmacy Bulk Package bag SmartPak® should be used only in patients who require a 1 gram dose and not any fraction thereof. Cefoxitin for Injection USP, Pharmacy Bulk Package bag SmartPak® should not be used in patients who require less than the 1 gram dose of cefoxitin. Cefoxitin for Injection, USP is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans . Its chemical name is sodium ( 6R,7S )-3-(hydroxymethyl)-7-methoxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate carbamate (ester). The empirical formula is C 16 H 16 N 3 NaO 7 S 2 , and the structural formula is: Cefoxitin for Injection contains approximately 53.8 mg (2.3 mEq) of sodium per gram of cefoxitin. Solutions of Cefoxitin for Injection, USP range from colorless to light amber in color. The pH of freshly constituted solutions usually ranges from 4.2 to 7.0. BEFORE ADMINISTRATION, THIS PHARMACY BULK PACKAGE REQUIRES RECONSTITUTION USING STERILE WATER FOR INJECTION, USP TO A CONCENTRATION OF 100 MG PER ML AND FURTHER DILUTION IN 50 ML OF A COMPATIBLE SOLUTION AND INFUSED INTRAVENOUSLY. THIS PRODUCT IS NOT INTENDED TO BE USED IN PEDIATRIC AND RENALLY IMPAIRED PATIENTS WHO REQUIRE LESS THAN A 1 GRAM DOSE. Each SmartPak ® Pharmacy Bulk Package…
How to use
Cefoxitin for Injection USP, Pharmacy Bulk Package bag SmartPak ® should be used only in patients who require a 1 gram dose and not any fraction thereof. Cefoxitin for Injection USP, Pharmacy Bulk Package bag SmartPak ® should not be used in patients who require less than the 1 gram dose of cefoxitin. THE INTENT OF THIS PHARMACY BULK PACKAGE IS FOR THE PREPARATION OF SOLUTIONS FOR INTRAVENOUS INFUSION ONLY. BEFORE ADMINISTRATION, THIS PHARMACY BULK PACKAGE REQUIRES RECONSTITUTION TO A CONCENTRATION OF 100 MG/ML AND FURTHER DILUTION IN 50 mL OF A COMPATIBLE SOLUTION. THIS IS A PHARMACY BULK PACKAGE – NOT FOR DIRECT INJECTION USE THIS FORMULATION OF CEFOXITIN ONLY IN PATIENTS WHO REQUIRE A 1 GRAM DOSE. Treatment Adults Cefoxitin for Injection, USP, Pharmacy Bulk Package bag SmartPak® should be used only in patients who require a 1 gram dose and not any fraction thereof. Cefoxitin for Injection USP, Pharmacy Bulk Package bag SmartPak® should not be used in patients who require less than the 1 gram dose of cefoxitin. The usual adult dosage range is 1 gram to 2 grams every six to eight hours. Dosage should be determined by susceptibility of the causative organisms, severity of infection, and the condition of the patient (see Table 1 for dosage guidelines). If C. trachomatis is a suspected pathogen, appropriate anti-chlamydial coverage should be added, because cefoxitin sodium has…
Side effects
Cefoxitin is generally well tolerated. The most common adverse reactions have been local reactions following intravenous injection. Other adverse reactions have been encountered infrequently. Local Reactions Thrombophlebitis has occurred with intravenous administration. Allergic Reactions Rash (including exfoliative dermatitis and toxic epidermal necrolysis), urticaria, flushing, pruritus, eosinophilia, fever, dyspnea, and other allergic reactions including anaphylaxis, interstitial nephritis and angioedema have been noted. Cardiovascula r Hypotension. Gastrointestinal Diarrhea, including documented pseudomembranous colitis, which can appear during or after antibiotic treatment. Nausea and vomiting have been reported rarely. Neuromuscular Possible exacerbation of myasthenia gravis. Blood Eosinophilia, leukopenia including granulocytopenia, neutropenia, anemia, including hemolytic anemia, thrombocytopenia, and bone marrow depression. A positive direct Coombs test may develop in some individuals, especially those with azotemia. Liver Function Transient elevations in SGOT, SGPT, serum LDH, and serum alkaline phosphatase; and jaundice have been reported. Renal Function Cefoxitin for Injection USP, Pharmacy Bulk Package bag, SmartPak ® should not be used in patients with renal impairment who require less than the 1 gram adult dose of cefoxitin. Elevations in serum creatinine and/or…
FDA Boxed Warning (the FDA’s most serious warning)
Boxed (black-box) warning — from the FDA label
PHARMACY BULK PACKAGE – NOT FOR DIRECT INFUSION THIS IS A PHARMACY BULK PACKAGE – NOT FOR DIRECT INJECTION
Warnings
Important safety information
Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including cefoxitin, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile . C. difficile produces toxins A and B, which contribute to the development of CDAD. Hypertoxin producing strains of C. difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary, since CDAD has been reported to occur over two months after the administration of antibacterial agents. If CDAD is suspected or confirmed, ongoing antibiotic use not directed against C. difficile may need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. difficile, and surgical evaluation should be instituted as clinically indicated.
Who should not take Cefoxitin in Plastic Container
Cefoxitin for Injection is contraindicated in patients who have shown hypersensitivity to cefoxitin and the cephalosporin group of antibiotics.
Overdose — what happens if you take too much
The acute intravenous LD 50 in the adult female mouse and rabbit was about 8 grams/kg and greater than 1 gram/kg, respectively. The acute intraperitoneal LD 50 in the adult rat was greater than 10 grams/kg.
U.S. Poison Control: call or text 1-800-222-1222 (free, 24/7). In an emergency call 911. From the FDA label; not medical advice.
Interactions
Increased nephrotoxicity has been reported following concomitant administration of cephalosporins and aminoglycoside antibiotics.
Drug class
How this class works, per Cephalosporins - StatPearls - NCBI Bookshelf.
May treat (source: NIH RxClass)
- abscess
- bacteroides infections
- infectious bone diseases
- clostridium infections
- escherichia coli infections
- gonorrhea
See how Cefoxitin in Plastic Container ranks — best-rated cephalosporin antibacterial for:
Dosage forms
Injectable
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Cefoxitin in Plastic Container treat?
- Cefoxitin in Plastic Container (Cefoxitin Sodium) may be used to treat abscess, bacteroides infections, infectious bone diseases, clostridium infections, escherichia coli infections, gonorrhea, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Cefoxitin in Plastic Container work?
- Cefoxitin in Plastic Container is a cephalosporin antibacterial. Cephalosporins kill bacteria by blocking the proteins they use to build their cell walls. Without an intact wall, the bacterium cannot hold its shape and dies, which clears the infection.
- Is there a coupon or discount for Cefoxitin in Plastic Container?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Cefoxitin in Plastic Container. To pay less, Cefoxitin in Plastic Container is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Cefoxitin in Plastic Container?
- Cefoxitin in Plastic Container is marketed by Samson Medcl. You can see Samson Medcl's full profile, rating, and other products on pharmaranks.
- Is Cefoxitin in Plastic Container a brand-name or generic drug?
- Cefoxitin in Plastic Container is a generic medication; its active ingredient is Cefoxitin Sodium. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
- Is Cefoxitin in Plastic Container available over the counter?
- No. Cefoxitin in Plastic Container is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Cefoxitin in Plastic Container come in?
- Cefoxitin in Plastic Container is currently marketed as injectable, per the FDA's National Drug Code Directory.
- What class of drug is Cefoxitin in Plastic Container?
- Cefoxitin in Plastic Container is classified as cephalosporin antibacterial, per the FDA's Established Pharmacologic Class.
- Is Cefoxitin in Plastic Container FDA-registered?
- Cefoxitin in Plastic Container is on record with the U.S. FDA under application number ANDA200938. You can verify this on its official FDA label.
- Is Cefoxitin in Plastic Container safe?
- There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Cefoxitin in Plastic Container. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
- What are the side effects of Cefoxitin in Plastic Container?
- Cefoxitin in Plastic Container's side effects are taken directly from its FDA label. From the label: Cefoxitin is generally well tolerated. The most common adverse reactions have been local reactions following intravenous injection. Other adverse reactions have been encountered infrequently. Local Reactions Thrombophlebitis has occurred with intravenous administration.… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.
Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
Reviews
No reviews yet. Be the first to write one.
People also viewed
cefixime
Cefixime
cefotan
Cefotetan Disodium
fetroja
Cefiderocol Sulfate Tosylate
cefazolin and dextrose
Cefazolin Sodium
cefazolin sodium
Cefazolin Sodium
cefepime hydrochloride
Cefepime Hydrochloride
Compare Cefoxitin in Plastic Container head-to-head
More cephalosporin antibacterial drugs
Browse medications A–Z
Research products from A to Z, compare independent ratings, and find alternatives.
cefoxitin in plastic container
New