chlor-trimeton
Chlor-Trimeton (Chlorpheniramine Maleate) is a histamine-1 receptor antagonist used to treat Perennial Allergic Rhinitis, Urticaria.
Chlorpheniramine Maleate · by Schering
Available as a generic: Chlorpheniramine Maleate
Key facts
- Active ingredient
- Chlorpheniramine Maleate
- Drug class
- Histamine-1 Receptor Antagonist
- Form
- Tablet, extended release, Injectable
- Strength
- Chlorpheniramine Maleate 2MG/5ML · Chlorpheniramine Maleate 4MG
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- perennial allergic rhinitis, urticaria
- Manufacturer
- Schering
- FDA application
- NDA006921
- Availability
- Discontinued (per FDA)
Drug class
How this class works, per Antihistamines - StatPearls - NCBI Bookshelf.
May treat (source: NIH RxClass)
See how Chlor-Trimeton ranks — best-rated histamine-1 receptor antagonist for:
Dosage forms
Tablet, extended release and Injectable
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Chlor-Trimeton treat?
- Chlor-Trimeton (Chlorpheniramine Maleate) may be used to treat perennial allergic rhinitis, urticaria, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Chlor-Trimeton work?
- Chlor-Trimeton is a histamine-1 receptor antagonist. H1 antihistamines work by blocking histamine, the chemical released during an allergic reaction, from attaching to H1 receptors. This prevents the sneezing, itching, runny nose, watery eyes, and hives that histamine would otherwise trigger.
- Is there a coupon or discount for Chlor-Trimeton?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Chlor-Trimeton. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Chlor-Trimeton?
- Chlor-Trimeton is marketed by Schering. You can see Schering's full profile, rating, and other products on pharmaranks.
- Is Chlor-Trimeton a brand-name or generic drug?
- Chlor-Trimeton is a brand-name product with the active ingredient Chlorpheniramine Maleate. Lower-cost generic equivalents containing Chlorpheniramine Maleate are available — ask your pharmacist.
- Is Chlor-Trimeton available over the counter?
- No. Chlor-Trimeton is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Chlor-Trimeton come in?
- Chlor-Trimeton is currently marketed as tablet, extended release and injectable, per the FDA's National Drug Code Directory.
- What class of drug is Chlor-Trimeton?
- Chlor-Trimeton is classified as histamine-1 receptor antagonist, per the FDA's Established Pharmacologic Class.
- Is Chlor-Trimeton FDA-registered?
- Chlor-Trimeton is on record with the U.S. FDA under application number NDA006921. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about CHLORPHENIRAMINE MALEATE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 6,814 reports naming CHLORPHENIRAMINE MALEATE — the active ingredient in Chlor-Trimeton, and the FDA flagged 91% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- nausea640 reports
- diarrhoea559 reports
- dyspnoea470 reports
- fatigue465 reports
- pyrexia453 reports
- vomiting447 reports
- pneumonia320 reports
- neutropenia304 reports
Read these as a signal, not a rate. A report does not mean CHLORPHENIRAMINE MALEATE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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