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ambisome

Pharmaranks rates Ambisome 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Ambisome (Amphotericin B) is a lipid-based polyene antifungal used to treat Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis, Cutaneous Candidiasis.

Amphotericin B · by Astellas

Available as a generic: Amphotericin B

72/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Amphotericin B
Form
Injectable
Strength
Amphotericin B 50MG/VIAL
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Astellas
FDA application
NDA050740

Drug class

May treat (source: NIH RxClass)

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

What does Ambisome treat?
Ambisome (Amphotericin B) may be used to treat aspergillosis, blastomycosis, chronic mucocutaneous candidiasis, cutaneous candidiasis, coccidioidomycosis, cystitis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How is Ambisome rated?
pharmaranks gives Ambisome a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Ambisome?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Ambisome. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Ambisome?
Ambisome is marketed by Astellas. You can see Astellas's full profile, rating, and other products on pharmaranks.
Is Ambisome a brand-name or generic drug?
Ambisome is a brand-name product with the active ingredient Amphotericin B. Lower-cost generic equivalents containing Amphotericin B are available — ask your pharmacist.
Is Ambisome available over the counter?
No. Ambisome is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Ambisome come in?
Ambisome is currently marketed as injectable, per the FDA's National Drug Code Directory.
What class of drug is Ambisome?
Ambisome is classified as lipid-based polyene antifungal, polyene antifungal, per the FDA's Established Pharmacologic Class.
Is Ambisome FDA-registered?
Ambisome is on record with the U.S. FDA under application number NDA050740. You can verify this on its official FDA label.
Has Ambisome been recalled by the FDA?
Ambisome has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Ambisome safe?
There's no single safe-or-not verdict. pharmaranks gives Ambisome a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about AMPHOTERICIN B

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 15,853 reports naming AMPHOTERICIN B — the active ingredient in Ambisome, and the FDA flagged 96% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • pyrexia850 reports
  • multiple organ dysfunction syndrome606 reports
  • acute kidney injury577 reports
  • sepsis519 reports
  • febrile neutropenia507 reports
  • respiratory failure487 reports
  • septic shock478 reports
  • pneumonia472 reports

Read these as a signal, not a rate. A report does not mean AMPHOTERICIN B caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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ambisome

72/100