AMBISOME vs CLOTRIMAZOLE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. AMBISOME and CLOTRIMAZOLE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AMBISOME	CLOTRIMAZOLE
Rating	70/100	70/100
Pharmacy pays	—	$0.21 /mL
Type	RX	RX
Active ingredient	AMPHOTERICIN B	CLOTRIMAZOLE
Manufacturer	Astellas	Fougera Pharms
Dosage forms	Injectable	Topical, Lozenge, Solution, Spray/Inhaler
Drug class	Lipid-Based Polyene Antifungal	Azole Antifungal
Boxed warning	None	None
Treats	Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis	Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis

ambisome clotrimazole

Rating

70/100

Pharmacy pays

—

$0.21 /mL

Type

Active ingredient

AMPHOTERICIN B

CLOTRIMAZOLE

Manufacturer

Astellas

Fougera Pharms

Dosage forms

Injectable

Topical, Lozenge, Solution, Spray/Inhaler

Drug class

Lipid-Based Polyene Antifungal

Azole Antifungal

Boxed warning

None

Treats

Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis

Get clotrimazole

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Frequently asked questions

Which is better-rated, Ambisome or Clotrimazole?

Ambisome and Clotrimazole are tied at 3.5 out of 5 by our independent rating.

What is the difference between Ambisome and Clotrimazole?

Ambisome contains Amphotericin B, while Clotrimazole contains Clotrimazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.