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Best treatments for chancroid

13 products may treat chancroid, spanning FDA drug classes such as macrolide, macrolide antimicrobial, tetracycline-class drug. The current highest-rated option is erythromycin ethylsuccinate. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 13 drugs we list for chancroid, 7 are available as lower-cost generics, spanning classes such as macrolide, macrolide antimicrobial, tetracycline-class drug. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for chancroid — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Top-rated picks for chancroid: 1. Erythromycin Ethylsuccinate · 2. Erythrocin · 3. Amzeeq

Top-rated treatments for chancroid, ranked by pharmaranks score
#DrugRatingPharmacy pays
170/100View →
260/100View →
3Not yet rated$11View →
4Not yet rated$11View →
5Not yet rated$43View →
6Not yet rated$43View →
7Not yet ratedView →
8Not yet ratedView →
9Not yet rated$11View →
10Not yet ratedView →

Full ranking · 13 treatments

#1 of 6 in Macrolide

erythromycin ethylsuccinate

PrescriptionFDA-sourced

70/100

Erythromycin Ethylsuccinate is a macrolide used to treat Acne Vulgaris, Campylobacter Infections, Chancroid, Chlamydia Infections.

(4 data points)
macrolidemacrolide antimicrobialacne vulgaris
Available online
View details →

erythrocin

PrescriptionFDA-sourced

60/100

Erythrocin (Erythromycin Lactobionate) is a macrolide used to treat Acne Vulgaris, Campylobacter Infections, Chancroid, Chlamydia Infections.

(88 data points)
macrolidemacrolide antimicrobialacne vulgaris
Available online
View details →

amzeeq

PrescriptionFDA-sourced

New

Amzeeq (Minocycline Hydrochloride) is a tetracycline-class drug used to treat Acne Vulgaris, Anthrax, Borrelia Infections, Chancroid.

tetracycline-class drugacne vulgarisanthrax

Pharmacy pays

From ~$5.35/30· 8 forms
View details →

arestin

PrescriptionFDA-sourced

New

Arestin (Minocycline Hydrochloride) is a tetracycline-class drug used to treat Acne Vulgaris, Anthrax, Borrelia Infections, Chancroid.

tetracycline-class drugacne vulgarisanthrax

Pharmacy pays

From ~$5.35/30· 8 forms
View details →

ceftriaxone

PrescriptionFDA-sourced

New

Ceftriaxone (Ceftriaxone Sodium) is a cephalosporin antibacterial used to treat Acinetobacter Infections, Infectious Bone Diseases, Chancroid, Clostridium Infections.

cephalosporin antibacterialacinetobacter infectionsbone diseases, infectious

Pharmacy pays

From ~$25.87/30· 4 forms Save up to 79% in class
View details →

ceftriaxone and dextrose in duplex container

PrescriptionFDA-sourced

New

Ceftriaxone and Dextrose in Duplex Container (Ceftriaxone Sodium) is a cephalosporin antibacterial used to treat Acinetobacter Infections, Infectious Bone Diseases, Chancroid, Clostridium Infections.

cephalosporin antibacterialacinetobacter infectionsbone diseases, infectious

Pharmacy pays

From ~$25.87/30· 4 forms Save up to 79% in class
View details →

Frequently asked

What treats chancroid?
Our catalog lists 13 products that may treat chancroid, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is erythromycin ethylsuccinate.
What is the best-rated treatment for chancroid?
By our independent recall-safety rating — not an efficacy measure — erythromycin ethylsuccinate ranks highest among the products we list for chancroid. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat chancroid?
Treatments for chancroid span FDA drug classes including macrolide, macrolide antimicrobial, tetracycline-class drug, cephalosporin antibacterial. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.