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Best Macrolide for chancroid

Top-rated pick: Erythromycin Ethylsuccinate — pharmaranks score 70/100, the highest of the 6 Macrolide drugs used for chancroid, ranked by our independent FDA recall-safety score. Compare them with all treatments for chancroid or the full Macrolide class. Not medical advice — always consult a professional.

Quick answer: Of the 6 macrolide drugs we rate for chancroid, none are yet flagged as generics in our price data, and most are suspension. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for chancroid; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated August 11, 2026·How we rate

How macrolide work

Macrolide antibiotics latch onto the bacterial ribosome's 50S subunit, the cell's protein-building machine, and block the growing protein chain from being assembled. Without the proteins they need, the bacteria stop multiplying, which lets the immune system clear the infection.

Source: Macrolides - StatPearls - NCBI Bookshelf

Top macrolide for chancroid: 1. Erythromycin Ethylsuccinate · 2. Erythrocin · 3. E.E.S.

Best-rated Macrolide for chancroid, ranked by pharmaranks score
#DrugRatingPharmacy pays
170/100View →
260/100View →
3Not yet ratedView →
4Not yet ratedView →
5Not yet ratedView →
6Not yet ratedView →

Full ranking · 6 drugs

#1 of 6 in Macrolide

erythromycin ethylsuccinate

PrescriptionFDA-sourced

70/100

Erythromycin Ethylsuccinate is a macrolide used to treat Acne Vulgaris, Campylobacter Infections, Chancroid, Chlamydia Infections.

(4 data points)
macrolidemacrolide antimicrobialacne vulgaris
Available online
View details →

erythrocin

PrescriptionFDA-sourced

60/100

Erythrocin (Erythromycin Lactobionate) is a macrolide used to treat Acne Vulgaris, Campylobacter Infections, Chancroid, Chlamydia Infections.

(88 data points)
macrolidemacrolide antimicrobialacne vulgaris
Available online
View details →

e.e.s.

PrescriptionFDA-sourced

New

E.E.S. (Erythromycin Ethylsuccinate) is a macrolide used to treat Acne Vulgaris, Campylobacter Infections, Chancroid, Chlamydia Infections.

macrolidemacrolide antimicrobialacne vulgaris
Available online
View details →

e.e.s. 400

PrescriptionFDA-sourced

New

E.E.S. 400 (Erythromycin Ethylsuccinate) is a macrolide used to treat Acne Vulgaris, Campylobacter Infections, Chancroid, Chlamydia Infections.

macrolidemacrolide antimicrobialacne vulgaris
Available online
View details →

eryped

PrescriptionFDA-sourced

New

Eryped (Erythromycin Ethylsuccinate) is a macrolide used to treat Acne Vulgaris, Campylobacter Infections, Chancroid, Chlamydia Infections.

macrolidemacrolide antimicrobialacne vulgaris
Available online
View details →

erythromycin lactobionate

PrescriptionFDA-sourced

New

Erythromycin Lactobionate is a macrolide used to treat Acne Vulgaris, Campylobacter Infections, Chancroid, Chlamydia Infections.

macrolidemacrolide antimicrobialacne vulgaris
Available online
View details →

Frequently asked

What is the best macrolide for chancroid?
By our independent recall-safety rating — not an efficacy measure — erythromycin ethylsuccinate ranks highest among Macrolide drugs used for chancroid. Always consult a professional.
Which macrolide drugs treat chancroid?
pharmaranks lists 6 Macrolide products used for chancroid, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.