Tetracyclines compared
Compare all 10 tetracyclines side by side, used for conditions such as anthrax, campylobacter infections, cholera. Tetracyclines are the Tetracycline-class Drug class. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is doryx mpc.
Top-rated tetracycline-class drug: 1. Doryx Mpc · 2. Doxycycline Hyclate · 3. Doxycycline
| Drug | Generic | Form | Status | Used for | Safety ratingFDA recall-based | Pharmacy pays |
|---|---|---|---|---|---|---|
| Doryx Mpc | Doxycycline Hyclate | Tablet | Prescription | Anthrax, Campylobacter Infections | 70/100 | $0 |
| Doxycycline Hyclate | — | Capsule | Prescription | Anthrax, Campylobacter Infections | 70/100 | $0 |
| Doxycycline | — | Capsule | Prescription | Anthrax, Campylobacter Infections | 64/100 | $0 |
| Amzeeq | Minocycline Hydrochloride | Topical | Prescription | Acne Vulgaris, Anthrax | Not yet rated | $11 |
| Arestin | Minocycline Hydrochloride | Powder | Prescription | Acne Vulgaris, Anthrax | Not yet rated | $11 |
| Emrosi | Minocycline Hydrochloride | Capsule | Prescription | Acne Vulgaris, Anthrax | Not yet rated | $11 |
| Minocin | Minocycline Hydrochloride | Injectable | Prescription | Acne Vulgaris, Anthrax | Not yet rated | $11 |
| Monodox | Doxycycline | Capsule | Prescription | Anthrax, Campylobacter Infections | Not yet rated | $0 |
| Oracea | Doxycycline | Capsule | Prescription | Anthrax, Campylobacter Infections | Not yet rated | $0 |
| Zilxi | Minocycline Hydrochloride | Topical | Prescription | Acne Vulgaris, Anthrax | Not yet rated | $11 |
The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.
Best tetracycline-class drug by condition
Full ranking · 10 drugs
- 170/100
doryx mpc
Doxycycline Hyclate
- 270/100
doxycycline hyclate
Doxycycline Hyclate
- 364/100
doxycycline
Doxycycline
- 4New
amzeeq
Minocycline Hydrochloride
- 5New
arestin
Minocycline Hydrochloride
- 6New
emrosi
Minocycline Hydrochloride
- 7New
minocin
Minocycline Hydrochloride
- 8New
monodox
Doxycycline
- 9New
oracea
Doxycycline
- 10New
zilxi
Minocycline Hydrochloride
Frequently asked questions
What is the Tetracycline-class Drug drug class?
Tetracycline-class Drug is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 10 Tetracycline-class Drug products, each independently rated.
Are all Tetracycline-class Drug drugs the same?
No. Tetracycline-class Drug drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.
Is "tetracyclines" the same as the Tetracycline-class Drug class?
Yes — "tetracyclines" is the everyday name for the Tetracycline-class Drug drug class. This page compares the 10 tetracyclines pharmaranks rates, with our independent FDA recall-safety score for each.
What conditions do Tetracycline-class Drug drugs treat?
Per NIH RxClass drug-classification data, Tetracycline-class Drug drugs are used for conditions including anthrax, campylobacter infections, cholera, granuloma inguinale, mycoplasma infections, psittacosis.
Which Tetracycline-class Drug drug is best-rated?
By our independent rating, doryx mpc currently ranks highest among Tetracycline-class Drug drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.
Sources: the Tetracycline-class Drug class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Tetracycline - StatPearls - NCBI Bookshelf. Ratings are pharmaranks’ independent FDA recall-safety analysis.