Best Nitrate Vasodilator for heart failure
Top-rated pick: Nitrostat — pharmaranks score 70/100, the highest of the 9 Nitrate Vasodilator drugs used for heart failure, ranked by our independent FDA recall-safety score. Compare them with all treatments for heart failure or the full Nitrate Vasodilator class. Not medical advice — always consult a professional.
Quick answer: Of the 9 nitrate vasodilator drugs we rate for heart failure, 7 are available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for heart failure; the right choice depends on your situation, so confirm it with your prescriber.
How nitrate vasodilator work
Nitrate vasodilators are converted in the body into nitric oxide, which relaxes the smooth muscle in blood vessel walls and widens them. This mainly opens up the veins, reducing how hard the heart must work and relieving chest pain.
Other drug classes for heart failure
Top nitrate vasodilator for heart failure: 1. Nitrostat · 2. Isordil · 3. Isosorbide Mononitrate
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Tablet | Generic | $4 | View → | |
| 2 | Not yet rated | Prescription | Tablet | Generic | $6 | View → | |
| 3 | Not yet rated | Prescription | Tablet | No data | — | View → | |
| 4 | Not yet rated | Prescription | Tablet | No data | — | View → | |
| 5 | Not yet rated | Prescription | Patch | Generic | $4 | View → | |
| 6 | Not yet rated | Prescription | Injectable | Generic | $4 | View → | |
| 7 | Not yet rated | Prescription | Spray/Inhaler | Generic | $4 | View → | |
| 8 | Not yet rated | Prescription | Spray/Inhaler | Generic | $4 | View → | |
| 9 | Not yet rated | Prescription | Spray/Inhaler | Generic | $4 | View → |
Full ranking · 9 drugs
nitrostat
PrescriptionFDA-sourced
Nitrostat (Nitroglycerin) is a nitrate vasodilator used to treat Angina Pectoris, Eclampsia, Fissure in Ano, Heart Failure.
Pharmacy pays
From ~$2.19/30· 8 formsisordil
PrescriptionFDA-sourced
Isordil (Isosorbide Dinitrate) is a nitrate vasodilator used to treat Angina Pectoris, Coronary Disease, Cyanosis, Gastroesophageal Reflux.
Pharmacy pays
From ~$5.30/30· 5 forms Save up to 30% in classisosorbide mononitrate
PrescriptionFDA-sourced
Isosorbide Mononitrate is a nitrate vasodilator used to treat Angina Pectoris, Coronary Disease, Cyanosis, Gastroesophageal Reflux.
Price varies
monoket
PrescriptionFDA-sourced
Monoket (Isosorbide Mononitrate) is a nitrate vasodilator used to treat Angina Pectoris, Coronary Disease, Cyanosis, Gastroesophageal Reflux.
Price varies
nitro-dur
Boxed warningPrescriptionFDA-sourced
Nitro-Dur (Nitroglycerin) is a nitrate vasodilator used to treat Angina Pectoris, Eclampsia, Fissure in Ano, Heart Failure.
Pharmacy pays
From ~$2.19/30· 8 formsnitroglycerin
PrescriptionFDA-sourced
Nitroglycerin is a nitrate vasodilator used to treat Angina Pectoris, Eclampsia, Fissure in Ano, Heart Failure.
Pharmacy pays
From ~$2.19/30· 8 formsnitrolingual
PrescriptionFDA-sourced
Nitrolingual (Nitroglycerin) is a nitrate vasodilator used to treat Angina Pectoris, Eclampsia, Fissure in Ano, Heart Failure.
Pharmacy pays
From ~$2.19/30· 8 formsnitrolingual pumpspray
PrescriptionFDA-sourced
Nitrolingual Pumpspray (Nitroglycerin) is a nitrate vasodilator used to treat Angina Pectoris, Eclampsia, Fissure in Ano, Heart Failure.
Pharmacy pays
From ~$2.19/30· 8 formsnitromist
PrescriptionFDA-sourced
Nitromist (Nitroglycerin) is a nitrate vasodilator used to treat Angina Pectoris, Eclampsia, Fissure in Ano, Heart Failure.
Pharmacy pays
From ~$2.19/30· 8 formsFrequently asked
- What is the best nitrate vasodilator for heart failure?
- By our independent recall-safety rating — not an efficacy measure — nitrostat ranks highest among Nitrate Vasodilator drugs used for heart failure. Always consult a professional.
- Which nitrate vasodilator drugs treat heart failure?
- pharmaranks lists 9 Nitrate Vasodilator products used for heart failure, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.