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Best Angiotensin Converting Enzyme Inhibitor for heart failure

Top-rated pick: Epaned — pharmaranks score 72/100, the highest of the 5 Angiotensin Converting Enzyme Inhibitor drugs used for heart failure, ranked by our independent FDA recall-safety score. Compare them with all treatments for heart failure or the full Angiotensin Converting Enzyme Inhibitor class. Not medical advice — always consult a professional.

Quick answer: Of the 5 angiotensin converting enzyme inhibitor drugs we rate for heart failure, 4 are available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for heart failure; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Top angiotensin converting enzyme inhibitor for heart failure: 1. Epaned · 2. Lotensin · 3. Qbrelis

Best-rated Angiotensin Converting Enzyme Inhibitor for heart failure, ranked by pharmaranks score
#DrugRatingPharmacy pays
172/100$0View →
272/100$2View →
372/100$1View →
4Not yet rated—View →
5Not yet rated$0View →

Full ranking · 5 drugs

#1 of 11 in Angiotensin Converting Enzyme Inhibitor

epaned

Boxed warning

PrescriptionFDA-sourced

72/100

Epaned (Enalapril Maleate) is an angiotensin converting enzyme inhibitor used to treat Rheumatoid Arthritis, Bartter Syndrome, Diabetic Nephropathies, Edema.

(4 data points)
angiotensin converting enzyme inhibitorarthritis, rheumatoidbartter syndrome

Pharmacy pays

From ~$0.07· 5 forms
View details →
#1 of 11 in Angiotensin Converting Enzyme Inhibitor

lotensin

Boxed warning

PrescriptionFDA-sourced

72/100

Lotensin (Benazepril Hydrochloride) is an angiotensin converting enzyme inhibitor used to treat Diabetic Nephropathies, Heart Failure, Hypertension, Left Ventricular Dysfunction.

(2 data points)
angiotensin converting enzyme inhibitordiabetic nephropathiesheart failure

Pharmacy pays

From ~$1.45/30· 4 forms Save up to 67% in class
View details →
#1 of 11 in Angiotensin Converting Enzyme Inhibitor

qbrelis

Boxed warning

PrescriptionFDA-sourced

72/100

Qbrelis (Lisinopril) is an angiotensin converting enzyme inhibitor used to treat Diabetic Nephropathies, Heart Failure, Hypertension, Myocardial Infarction.

(4 data points)
angiotensin converting enzyme inhibitordiabetic nephropathiesheart failure

Pharmacy pays

From ~$0.43/30· 6 forms
View details →

quinapril hydrochloride

Boxed warning

PrescriptionFDA-sourced

New

Quinapril Hydrochloride is an angiotensin converting enzyme inhibitor used to treat Diabetic Nephropathies, Heart Failure, Hypertension, Left Ventricular Dysfunction.

angiotensin converting enzyme inhibitordiabetic nephropathiesheart failure

Price varies

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vasotec

Boxed warning

PrescriptionFDA-sourced

New

Vasotec (Enalapril Maleate) is an angiotensin converting enzyme inhibitor used to treat Rheumatoid Arthritis, Bartter Syndrome, Diabetic Nephropathies, Edema.

angiotensin converting enzyme inhibitorarthritis, rheumatoidbartter syndrome

Pharmacy pays

From ~$0.07· 5 forms
View details →

Frequently asked

What is the best angiotensin converting enzyme inhibitor for heart failure?
By our independent recall-safety rating — not an efficacy measure — epaned ranks highest among Angiotensin Converting Enzyme Inhibitor drugs used for heart failure. Always consult a professional.
Which angiotensin converting enzyme inhibitor drugs treat heart failure?
pharmaranks lists 5 Angiotensin Converting Enzyme Inhibitor products used for heart failure, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.

Where this ranking comes from

Our score is computed from public FDA data — not from opinion, sponsorship or user votes. How we rate.