Skip to content
ppharmaranks
Menu
Avoid alcohol

Can you drink alcohol with Mirtazapine (Remeron)?

Here is what the FDA-approved label for Mirtazapine (Remeron) actually says about alcohol — transcribed, not a secondhand guess.

By the pharmaranks editorial teamReviewed against the FDA drug label for Mirtazapine sourcesUpdated Jul 21, 2026How we research

Mirtazapine and alcohol, from the label

The label addresses alcohol directly and says to avoid it. In its drug-interactions table ("Benzodiazepines and Alcohol"), it states that drinking alcohol while taking mirtazapine increases the impairment of cognitive and motor skills produced by mirtazapine alone, and it instructs patients to avoid concomitant use. Clinical Pharmacology confirms this: in study subjects, alcohol had minimal effect on mirtazapine plasma levels, but the cognitive and motor impairment from mirtazapine was additive with that from alcohol. The Patient Counseling section likewise advises patients to avoid drinking alcohol during treatment. This is an additive CNS/psychomotor-impairment warning, not a disulfiram-like reaction.

Frequently asked questions

Can you drink alcohol while taking Mirtazapine?

The FDA label advises against it. Mirtazapine and alcohol interact (summarized above), and the label directs avoiding or minimizing alcohol while taking it. Confirm with your prescriber or pharmacist for your situation.

How long after Mirtazapine can you drink alcohol?

There is no single number that fits every drug, and the safe gap depends on why the two interact — a drug that adds to alcohol's sedation is a concern while it is still in your system, while a disulfiram-type reaction (like metronidazole's) is avoided during treatment and for a labeled period after the last dose. Follow the specific guidance above and ask the prescriber who wrote the prescription; do not guess a window.

What happens if you drink on Mirtazapine?

The specific effect is described above, from the label. In most cases it means additive drowsiness and impaired coordination, or added strain on an organ the drug already affects — worse with more alcohol and in older adults. If you feel unwell after mixing the two, stop drinking and seek advice; call 911 for trouble breathing, fainting, or a rapid irregular heartbeat.

More guides for Mirtazapine

Source

Mirtazapine Tablets — DailyMed Label

Other drugs: Alprazolam · Baclofen · Bupropion · Buspirone · Clonazepam · Clonidine · Cyclobenzaprine · Diazepam · Duloxetine · Fluoxetine · Hydrocodone · Hydroxyzine · Lorazepam · Methylphenidate · all drugs.

The alcohol interaction is transcribed from this drug’s FDA-approved label. This is general reference information, not medical advice. If you drink and take medication regularly, talk to your prescriber or pharmacist about your specific situation.