Skip to content
ppharmaranks
Menu

Can you drink alcohol with Buspirone (Buspar)?

Here is what the FDA-approved label for Buspirone (Buspar) actually says about alcohol — transcribed, not a secondhand guess.

By the pharmaranks editorial teamReviewed against the FDA drug label for Buspirone sourcesUpdated Jul 21, 2026How we research

Buspirone and alcohol, from the label

The label addresses alcohol. It notes that formal interaction studies show buspirone does not increase alcohol-induced impairment of motor and mental performance (buspirone is not a benzodiazepine and does not carry the additive-sedation warning those drugs do). Even so, the label states it is prudent to avoid using alcohol together with buspirone. Patients are also told to inform their physician about any alcohol use during treatment.

Frequently asked questions

Can you drink alcohol while taking Buspirone?

The FDA label advises against it. Buspirone and alcohol interact (summarized above), and the label directs avoiding or minimizing alcohol while taking it. Confirm with your prescriber or pharmacist for your situation.

How long after Buspirone can you drink alcohol?

There is no single number that fits every drug, and the safe gap depends on why the two interact — a drug that adds to alcohol's sedation is a concern while it is still in your system, while a disulfiram-type reaction (like metronidazole's) is avoided during treatment and for a labeled period after the last dose. Follow the specific guidance above and ask the prescriber who wrote the prescription; do not guess a window.

What happens if you drink on Buspirone?

The specific effect is described above, from the label. In most cases it means additive drowsiness and impaired coordination, or added strain on an organ the drug already affects — worse with more alcohol and in older adults. If you feel unwell after mixing the two, stop drinking and seek advice; call 911 for trouble breathing, fainting, or a rapid irregular heartbeat.

More guides for Buspirone

Source

Buspirone Hydrochloride Tablets — FDA label (DailyMed)

Other drugs: Alprazolam · Baclofen · Bupropion · Clonazepam · Clonidine · Cyclobenzaprine · Diazepam · Duloxetine · Fluoxetine · Hydrocodone · Hydroxyzine · Lorazepam · Methylphenidate · Mirtazapine · all drugs.

The alcohol interaction is transcribed from this drug’s FDA-approved label. This is general reference information, not medical advice. If you drink and take medication regularly, talk to your prescriber or pharmacist about your specific situation.