xuriden
Xuriden (Uridine Triacetate) is a pyrimidine analog used to treat Drug Overdose.
Uridine Triacetate · by Btg Intl
Key facts
- Active ingredient
- Uridine Triacetate
- Drug class
- Pyrimidine Analog
- Form
- Powder
- Strength
- Uridine Triacetate 2GM/PACKET
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- drug overdose
- Manufacturer
- Btg Intl
- FDA application
- NDA208169
What is Xuriden?
From the FDA label:XURIDEN (uridine triacetate) oral granules is a pyrimidine analog indicated for uridine replacement therapy. Uridine triacetate has the chemical designation (2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione. The molecular weight is 370.3 and it has an empirical formula of C 15 H 18 N 2 O 9 . The structural formula is: Each single-use 2-gram packet of XURIDEN orange-flavored oral granules (95% w/w) contains 2 grams of uridine triacetate and the following inactive ingredients: ethylcellulose (0.062 grams), Opadry Clear [proprietary dispersion of hydroxypropylmethylcellulose and Macrogol] (0.015 grams), and natural orange juice flavor (0.026 grams). Chemical Structure
How to use
Recommended Dosage ( 2.1 ): The starting dosage is 60 mg/kg once daily; the dose may be increased to120 mg/kg (not to exceed 8 grams) once daily for insufficient efficacy. See the full prescribing information for 60 mg/kg and 120 mg/kg weight-based dosing tables. Preparation and Administration ( 2.2 ) Measure the dose using either a scale accurate to at least 0.1 gram, or a graduated teaspoon, accurate to the fraction of the dose to be administered. Administer the dose with food (applesauce, pudding or yogurt) or in milk or infant formula. See full prescribing information for preparation and administration instructions. 2.1 Recommended Dosage The recommended starting dosage of oral XURIDEN is 60 mg/kg once daily. Increase the dosage of XURIDEN to 120 mg/kg (not to exceed 8 grams) once daily for insufficient efficacy, such as occurrence of one of the following: Levels of orotic acid in urine remain above normal or increase above the usual or expected range for the patient Laboratory values (e.g., red blood cell or white blood cell indices) affected by hereditary orotic aciduria show evidence of worsening Worsening of other signs or symptoms of the disease The XURIDEN dose to be administered at the 60 mg/kg and 120 mg/kg dose levels by body-weight is presented in Tables 1 and 2. A 2 gram packet of XURIDEN contains approximately ¾ teaspoon of XURIDEN. Therefore, in the tables…
Side effects
No adverse reactions were reported in clinical trials with XURIDEN in patients with hereditary orotic aciduria. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact BTG International Inc. at (1-877-377-3784) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions and using a wide range of doses, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The safety of XURIDEN was assessed in 4 patients with hereditary orotic aciduria ranging in age from 3 to 19 years (3 male, 1 female) who received 60 mg/kg of XURIDEN once daily for six weeks. All patients continued to receive XURIDEN for at least 24 months at dosages of up to 120 mg/kg once daily. No adverse reactions were reported with XURIDEN.
Warnings
Important safety information
None
Who should not take Xuriden
None None ( 4 )
Drug class
May treat (source: NIH RxClass)
See how Xuriden ranks — best-rated pyrimidine analog for:
Dosage forms
Powder
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Xuriden treat?
- Xuriden (Uridine Triacetate) may be used to treat drug overdose, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- Is there a coupon or discount for Xuriden?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Xuriden. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Xuriden?
- Xuriden is marketed by Btg Intl. You can see Btg Intl's full profile, rating, and other products on pharmaranks.
- Is Xuriden a brand-name or generic drug?
- Xuriden is a brand-name product with the active ingredient Uridine Triacetate.
- Is Xuriden available over the counter?
- No. Xuriden is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Xuriden come in?
- Xuriden is currently marketed as powder, per the FDA's National Drug Code Directory.
- What class of drug is Xuriden?
- Xuriden is classified as pyrimidine analog, per the FDA's Established Pharmacologic Class.
- Is Xuriden FDA-registered?
- Xuriden is on record with the U.S. FDA under application number NDA208169. You can verify this on its official FDA label.
- Is Xuriden safe?
- There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Xuriden. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
- What are the side effects of Xuriden?
- Xuriden's side effects are taken directly from its FDA label. From the label: No adverse reactions were reported in clinical trials with XURIDEN in patients with hereditary orotic aciduria. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact BTG International Inc. at (1-877-377-3784) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.
Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
Reviews
No reviews yet. Be the first to write one.
People also viewed
Compare Xuriden head-to-head
Browse medications A–Z
Research products from A to Z, compare independent ratings, and find alternatives.
xuriden
New