Uridine Triacetate: uses, dosing, side effects & brands
Uridine Triacetate is a pyrimidine analog sold in the U.S. under 2 brand and generic names, for drug overdose. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Drug class
- Pyrimidine Analog
- Treats
- Drug Overdose
- Available as
- Powder
- Sold as
- 2 products — Vistogard and Xuriden
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
How uridine triacetate is dosed
From the FDA label for Vistogard (application NDA208159). Other uridine triacetate products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.
Recommended Dosage Adults : 10 grams (1 packet) orally every 6 hours for 20 doses, without regard to meals. ( 2.1 ) Pediatric : 6.2 grams/m 2 of body surface area (not to exceed 10 grams per dose) orally every 6 hours for 20 doses, without regard to meals. See the full prescribing information for body surface area-based dosing. ( 2.1 ) Preparation and Administration Pediatric : Measure the dose using either a scale accurate to at least 0.1 gram, or a graduated teaspoon accurate to ¼ teaspoon. ( 2.1 ) Mix each VISTOGARD dose with 3 to 4 ounces of soft foods such as applesauce, pudding or yogurt and ingest within 30 minutes of mixing. Do not chew the VISTOGARD granules. Drink at least 4 ounces of water. ( 2.2 ) If a patient vomits within 2 hours of taking a dose of VISTOGARD, initiate another complete dose as soon as possible after the vomiting episode. Administer the next dose at the regularly scheduled time. ( 2.2 ) If a patient misses a dose at the scheduled time, administer that dose of VISTOGARD as soon as possible. Administer the next dose at the regularly scheduled time. ( 2.2 ) Administer VISTOGARD via a nasogastric tube (NG tube) or gastrostomy tube (G-Tube) when necessary (e.g., severe mucositis or coma). ( 2.2 ) 2.1 Recommended Dosage Adults: 10 grams (1 packet) orally every 6 hours for 20 doses, without regard to meals. Pediatric: 6.2 grams/m 2 of body surface area…
Uridine Triacetate side effects
Adverse reactions occurring in >2% of patients receiving VISTOGARD included vomiting, nausea, and diarrhea. ( 6 ) To report SUSPECTED ADVERSE REACTIONS, contact BTG International Inc at (1-877-377-3784) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions and using a wide range of doses, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The safety of VISTOGARD was assessed in 135 patients (median age 59 years, 56% male) treated in 2 single-arm, open-label, multi-center trials. VISTOGARD was administered at 10 grams orally every 6 hours for 20 doses or at a body surface area adjusted dosage of 6.2 grams/m 2 /dose for 20 doses in four patients between 1 and 7 years of age. The median duration of exposure was 4.8 days, with a median of 20 doses (range 1 to 23). VISTOGARD was discontinued for adverse reactions in two (1.4%) patients. Serious adverse reactions and Grade ≥3 adverse reactions were seen in one patient receiving VISTOGARD (Grade 3 nausea and vomiting). Table 2 summarizes the adverse reactions that occurred in greater than 2% of patients in Studies 1 and 2 combined. Table 2 Adverse Reactions in > 2% of Patients Receiving VISTOGARD in…
Who shouldn’t take uridine triacetate
None. None. ( 4 )
Every uridine triacetate product we track (2)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | Not yet rated | Prescription | Powder | No data | — | View → | |
| 2 | Not yet rated | Prescription | Powder | No data | — | View → |
Can you crush or split uridine triacetate?
At least one uridine triacetateproduct is labelled to be swallowed whole — crushing an extended-release tablet releases the whole day’s dose at once. Which applies depends on the form you were given.
What each uridine triacetate label says about crushing, splitting and chewingWhat people report to the FDA about uridine triacetate
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 18 reports naming uridine triacetate, and the FDA flagged 78% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- mucosal inflammation4 reports
- thrombocytopenia4 reports
- diarrhoea3 reports
- dysphagia3 reports
- gastroenteritis3 reports
- neutropenic colitis3 reports
- stomatitis3 reports
- neutropenia2 reports
Read these as a signal, not a rate. A report does not mean uridine triacetate caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.
Source: openFDA drug/event (FAERS), retrieved August 26, 2026.
Related calculators
Frequently asked questions
What is uridine triacetate?
VISTOGARD oral granules contain the active ingredient uridine triacetate which is a pyrimidine analog.
What kind of drug is uridine triacetate?
The FDA classifies uridine triacetate as a pyrimidine analog. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.
Can you take uridine triacetate with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run uridine triacetate against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is uridine triacetate sold under?
We track 2 uridine triacetate-containing products in the U.S.: Vistogard and Xuriden. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does uridine triacetate come in?
Across the brands we track, uridine triacetate is currently marketed as powder, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic uridine triacetate?
We do not currently list a generic-labelled uridine triacetate product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Uridine Triacetate: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/uridine-triacetate
- MLA
- “Uridine Triacetate: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/uridine-triacetate.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for uridine triacetate on DailyMed (NIH) ↗.