tyrvaya

What is Tyrvaya?

From the FDA label:TYRVAYA nasal spray contains varenicline which is a partial nicotinic acetylcholine receptor agonist of α4β2, α4α6β2, α3β4, and α3α5β4 receptors and a full α7 receptor agonist. Varenicline, as the tartrate salt, is a powder which is a white to off-white to slightly yellow solid whose chemical name is 7,8,9,10-tetrahydro-6,10-methano-6 H -pyrazino[2,3-h][3]benzazepine, (2 R ,3 R )-2,3-dihydroxybutanedioate (1:1). It is highly soluble in water. Varenicline tartrate has a molecular weight of 361.35 Daltons and a molecular formula of C 13 H 13 N 3 ⋅ C 4 H 6 O 6 . The chemical structure is: TYRVAYA (varenicline solution) nasal spray is formulated for intranasal use as a clear 0.6 mg/mL strength solution, at pH 6.4. After priming [see Dosage and Administration ( 2.2 )] , each actuation delivers a 0.05 mL spray containing 0.03 mg varenicline free base, equivalent to 0.05 mg of varenicline tartrate. The formulation also contains the following inactive ingredients: sodium phosphate dibasic heptahydrate, monobasic sodium phosphate anhydrous, sodium chloride, sodium hydroxide and/or hydrochloric acid (to adjust pH) and water for injection. The chemical structure

How to use

Side effects

Who should not take Tyrvaya

Frequently asked questions

How does Tyrvaya work?

Tyrvaya is a cholinergic receptor agonist. Cholinergic receptor agonists mimic acetylcholine and switch on its receptors, triggering the body's "rest and digest" responses. This boosts effects like saliva and tear flow, bladder and bowel emptying, and pupil constriction.

How much does Tyrvaya cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $12.08 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Tyrvaya?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Tyrvaya. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Tyrvaya?

Tyrvaya is marketed by Oyster Point Pharma. You can see Oyster Point Pharma's full profile, rating, and other products on pharmaranks.

Is Tyrvaya a brand-name or generic drug?

Tyrvaya is a brand-name product with the active ingredient Varenicline Tartrate. Lower-cost generic equivalents containing Varenicline Tartrate are available — ask your pharmacist.

Is Tyrvaya available over the counter?

No. Tyrvaya is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Tyrvaya come in?

Tyrvaya is currently marketed as spray/inhaler, per the FDA's National Drug Code Directory.

What class of drug is Tyrvaya?

Tyrvaya is classified as cholinergic receptor agonist, partial cholinergic nicotinic agonist, per the FDA's Established Pharmacologic Class.

Is Tyrvaya FDA-registered?

Tyrvaya is on record with the U.S. FDA under application number NDA213978. You can verify this on its official FDA label.

Is Tyrvaya safe?

There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Tyrvaya. Review its FDA-label side effects and warnings below, and always consult a licensed professional.

What are the side effects of Tyrvaya?

Tyrvaya's side effects are taken directly from its FDA label. From the label: The most common adverse reaction reported in 82% of patients was sneezing. Events that were reported in 5-16% of patients were cough, throat irritation, and instillation-site (nose) irritation. ( 6 ) To report SUSPECTED ADVERSE REACTIONS,… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.