QLOSI vs TYRVAYA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. QLOSI and TYRVAYA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	QLOSI	TYRVAYA
Rating	New	New
Pharmacy pays	$0.38 /mL	~$12.08 /30
Type	RX	RX
Active ingredient	PILOCARPINE HYDROCHLORIDE	VARENICLINE TARTRATE
Manufacturer	Orasis Pharms	Oyster Point Pharma
Dosage forms	Solution	Spray/Inhaler
Drug class	Cholinergic Receptor Agonist	Cholinergic Receptor Agonist
Boxed warning	None	None
Treats	Head and Neck Neoplasms, Xerostomia, Angle-Closure Glaucoma	—

qlosi tyrvaya

Rating

New

Pharmacy pays

$0.38 /mL

~$12.08 /30

Type

Active ingredient

PILOCARPINE HYDROCHLORIDE

VARENICLINE TARTRATE

Manufacturer

Orasis Pharms

Oyster Point Pharma

Dosage forms

Solution

Spray/Inhaler

Drug class

Cholinergic Receptor Agonist

Boxed warning

None

Treats

Head and Neck Neoplasms, Xerostomia, Angle-Closure Glaucoma

—

Frequently asked questions

What is the difference between Qlosi and Tyrvaya?

Qlosi contains Pilocarpine Hydrochloride, while Tyrvaya contains Varenicline Tartrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.