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trental

Trental (Pentoxifylline) is a blood viscosity reducer used to treat Brain Ischemia, Diabetic Angiopathies, Diabetic Neuropathies, Gangrene.

Pentoxifylline · by Validus Pharms

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated August 19, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
Lower-cost optionsSave up to 53%
This medication~$7.19/30
Cheapest in class · cymbalta~$3.41/30
See FDA-approved alternatives

Key facts

Active ingredient
Pentoxifylline
Form
Tablet, extended release
Strength
Pentoxifylline 400MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
May treat
brain ischemia, diabetic angiopathies, diabetic neuropathies
Manufacturer
Validus Pharms
What the pharmacy pays
~$7.19 for 30 — not your price
FDA application
NDA018631
Availability
Discontinued (per FDA)

Drug class

May treat (source: NIH RxClass)

Dosage forms

Tablet, extended release

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Trental treat?
Trental (Pentoxifylline) may be used to treat brain ischemia, diabetic angiopathies, diabetic neuropathies, gangrene, intermittent claudication, thrombosis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How much does Trental cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $7.19 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Cymbalta — about $3.41 on the same basis.
Is there a coupon or discount for Trental?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Trental. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Trental?
Trental is marketed by Validus Pharms. You can see Validus Pharms's full profile, rating, and other products on pharmaranks.
Is Trental a brand-name or generic drug?
Trental is a brand-name product with the active ingredient Pentoxifylline.
Is Trental available over the counter?
No. Trental is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Trental come in?
Trental is currently marketed as tablet, extended release, per the FDA's National Drug Code Directory.
What class of drug is Trental?
Trental is classified as blood viscosity reducer, per the FDA's Established Pharmacologic Class.
Is Trental FDA-registered?
Trental is on record with the U.S. FDA under application number NDA018631. You can verify this on its official FDA label.
Has Trental been recalled by the FDA?
Trental has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Trental safe?
There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Trental. Review its FDA-label side effects and warnings below, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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