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MEXILETINE HYDROCHLORIDE vs TRENTAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. MEXILETINE HYDROCHLORIDE and TRENTAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

~$8.44 /30
~$7.19 /30

Type

RX
RX

Active ingredient

MEXILETINE HYDROCHLORIDE
PENTOXIFYLLINE

Dosage forms

Capsule
Tablet, extended release

Drug class

Antiarrhythmic
Blood Viscosity Reducer

Boxed warning

None
None

Treats

Diabetic Neuropathies, Ventricular Fibrillation, Ventricular Premature Complexes
Brain Ischemia, Diabetic Angiopathies, Diabetic Neuropathies

Frequently asked questions

Which is cheaper, Mexiletine Hydrochloride or Trental?

Trental costs pharmacies less to acquire — about $7.19 vs $8.44 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Mexiletine Hydrochloride and Trental?

Mexiletine Hydrochloride contains Mexiletine Hydrochloride, while Trental contains Pentoxifylline — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.