tagrisso
Pharmaranks rates Tagrisso 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Tagrisso (Osimertinib Mesylate) is a kinase inhibitor used to treat Non-Small-Cell Lung Carcinoma.
Osimertinib Mesylate · by Astrazeneca
Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →
Key facts
- Active ingredient
- Osimertinib Mesylate
- Drug class
- Kinase Inhibitor
- Form
- Tablet
- Strength
- Osimertinib Mesylate EQ 40MG Base · Osimertinib Mesylate EQ 80MG Base
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- non-small-cell lung carcinoma
- Manufacturer
- Astrazeneca
- FDA application
- NDA208065
Drug class
How this class works, per Tyrosine Kinase Inhibitors - StatPearls - NCBI Bookshelf.
May treat (source: NIH RxClass)
See how Tagrisso ranks — best-rated kinase inhibitor for:
Dosage forms
Tablet
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
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Frequently asked questions
- What does Tagrisso treat?
- Tagrisso (Osimertinib Mesylate) may be used to treat non-small-cell lung carcinoma, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Tagrisso work?
- Tagrisso is a kinase inhibitor. Kinase inhibitors block protein kinases, the enzymes that relay 'grow and divide' signals inside cells. By shutting down the overactive kinase signals that a tumor depends on, they help slow or stop cancer cells from multiplying.
- How is Tagrisso rated?
- pharmaranks gives Tagrisso a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
- Is there a coupon or discount for Tagrisso?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Tagrisso. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Tagrisso?
- Tagrisso is marketed by Astrazeneca. You can see Astrazeneca's full profile, rating, and other products on pharmaranks.
- Is Tagrisso a brand-name or generic drug?
- Tagrisso is a brand-name product with the active ingredient Osimertinib Mesylate.
- Is Tagrisso available over the counter?
- No. Tagrisso is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Tagrisso come in?
- Tagrisso is currently marketed as tablet, per the FDA's National Drug Code Directory.
- What class of drug is Tagrisso?
- Tagrisso is classified as kinase inhibitor, per the FDA's Established Pharmacologic Class.
- Is Tagrisso FDA-registered?
- Tagrisso is on record with the U.S. FDA under application number NDA208065. You can verify this on its official FDA label.
- Has Tagrisso been recalled by the FDA?
- Tagrisso has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
- Is Tagrisso safe?
- There's no single safe-or-not verdict. pharmaranks gives Tagrisso a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about OSIMERTINIB MESYLATE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 578 reports naming OSIMERTINIB MESYLATE — the active ingredient in Tagrisso, and the FDA flagged 100% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- myelosuppression252 reports
- hepatic function abnormal37 reports
- platelet count decreased31 reports
- malignant neoplasm progression28 reports
- interstitial lung disease24 reports
- decreased appetite23 reports
- nausea23 reports
- drug resistance22 reports
Read these as a signal, not a rate. A report does not mean OSIMERTINIB MESYLATE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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tagrisso
70/100