Kinase Inhibitor drugs compared

Compare all 43 Kinase Inhibitor drugs side by side, used for conditions such as idiopathic pulmonary fibrosis, leukemia, lymphoid, leukemia, myeloid. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is ofev.

Top-rated kinase inhibitor: 1. Ofev · 2. Sprycel · 3. Afinitor

Kinase Inhibitor drugs compared side by side, with pharmaranks' FDA recall-safety rating
Drug	Generic	Form	Status	Used for	Safety ratingFDA recall-based	Pharmacy pays
Ofev	Nintedanib Esylate	Capsule	Prescription	Idiopathic Pulmonary Fibrosis	72/100	—
Sprycel	Dasatinib	Tablet	Prescription	Leukemia, Lymphoid, Leukemia, Myeloid	72/100	$839
Afinitor	Everolimus	Tablet	Prescription	—	70/100	$229
Calquence	Acalabrutinib	Capsule	Prescription	Lymphoma, Mantle-Cell	70/100	—
Cotellic	Cobimetinib Fumarate	Tablet	Prescription	Melanoma	70/100	—
Danziten	Nilotinib Tartrate	Tablet	Prescription	Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase	70/100	—
Everolimus	—	Tablet	Prescription	—	70/100	$229
Gleevec	Imatinib Mesylate	Tablet	Prescription	Leukemia, Lymphoid, Leukemia, Myeloid	70/100	$26
Kisqali	Ribociclib Succinate	Tablet	Prescription	Breast Neoplasms	70/100	—
Koselugo	Selumetinib Sulfate	Capsule	Prescription	Neurofibromatosis 1	70/100	—
Mekinist	Trametinib Dimethyl Sulfoxide	Solution	Prescription	Carcinoma, Non-Small-Cell Lung, Melanoma	70/100	—
Tabrecta	Capmatinib Hydrochloride	Tablet	Prescription	Carcinoma, Non-Small-Cell Lung	70/100	—

The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.

Best kinase inhibitor by condition

for idiopathic pulmonary fibrosis for lymphoid leukemia for myeloid leukemia for mantle-cell lymphoma for melanoma for accelerated phase myeloid leukemia

Full ranking · 43 drugs

Frequently asked questions

What is the Kinase Inhibitor drug class?

Kinase Inhibitor is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 43 Kinase Inhibitor products, each independently rated.

Are all Kinase Inhibitor drugs the same?

No. Kinase Inhibitor drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.

What conditions do Kinase Inhibitor drugs treat?

Per NIH RxClass drug-classification data, Kinase Inhibitor drugs are used for conditions including idiopathic pulmonary fibrosis, leukemia, lymphoid, leukemia, myeloid, lymphoma, mantle-cell, melanoma, leukemia, myeloid, accelerated phase.

Which Kinase Inhibitor drug is best-rated?

By our independent rating, ofev currently ranks highest among Kinase Inhibitor drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.

Sources: the Kinase Inhibitor class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Tyrosine Kinase Inhibitors - StatPearls - NCBI Bookshelf. Ratings are pharmaranks’ independent FDA recall-safety analysis.