sitavig
Sitavig (Acyclovir) is a herpes simplex virus nucleoside analog dna polymerase inhibitor used to treat Chickenpox, Herpes Genitalis, Herpes Labialis, Herpes Zoster Ophthalmicus.
Acyclovir · by Ligand Pharms
Available as a generic: Acyclovir
Key facts
- Active ingredient
- Acyclovir
- Form
- Tablet
- Strength
- Acyclovir 50MG
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- chickenpox, herpes genitalis, herpes labialis
- Manufacturer
- Ligand Pharms
- Half-life
- about 2.5 to 3.3 hours (how long it stays in your system)
- What the pharmacy pays
- ~$4.83 for 30 — not your price
- FDA application
- NDA203791
- Availability
- Discontinued (per FDA)
How long does Acyclovir stay in your body?
The elimination half-life of acyclovir is about 2.5 to 3.3 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Acyclovir is cleared almost entirely by the kidneys — 62% to 91% of a dose leaves the body as unchanged drug — so the half-life tracks kidney function closely. The IV label tabulates it by creatinine clearance: 2.5 hours at CrCl above 80, 3 hours at 50–80, 3.5 hours at 15–50, and 19.5 hours in anuric patients, roughly an eightfold increase in severe kidney failure. Older adults reach higher plasma levels than younger adults, which the label attributes to age-related decline in renal function rather than to age itself; no separate geriatric half-life is given. There is no active metabolite that outlasts the parent — the only major urinary metabolite named is 9-carboxymethoxymethylguanine (up to 14.1% of the dose), and the label does not report a half-life for it. Liver impairment is not addressed in the pharmacokinetics section, consistent with renal rather than hepatic elimination. No extended-release oral acyclovir is marketed in the US; tablets, capsules, oral suspension and IV all reflect the same short elimination half-life. One drug effect worth naming: probenecid taken with acyclovir lengthens the mean half-life and raises overall exposure.
This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Acyclovir Tablets, USP — FDA prescribing information, Clinical Pharmacology (DailyMed).
Drug class
- Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor
- Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor
- Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor
May treat (source: NIH RxClass)
- chickenpox
- herpes genitalis
- herpes labialis
- herpes zoster ophthalmicus
- aids-related opportunistic infections
- epstein-barr virus infections
See how Sitavig ranks — best-rated herpes simplex virus nucleoside analog dna polymerase inhibitor for:
Dosage forms
Tablet
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Sitavig treat?
- Sitavig (Acyclovir) may be used to treat chickenpox, herpes genitalis, herpes labialis, herpes zoster ophthalmicus, AIDS-related opportunistic infections, epstein-barr virus infections, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How much does Sitavig cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $4.83 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
- Is there a coupon or discount for Sitavig?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Sitavig. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Sitavig?
- Sitavig is marketed by Ligand Pharms. You can see Ligand Pharms's full profile, rating, and other products on pharmaranks.
- Is Sitavig a brand-name or generic drug?
- Sitavig is a brand-name product with the active ingredient Acyclovir. Lower-cost generic equivalents containing Acyclovir are available — ask your pharmacist.
- Is Sitavig available over the counter?
- No. Sitavig is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Sitavig come in?
- Sitavig is currently marketed as tablet, per the FDA's National Drug Code Directory.
- What class of drug is Sitavig?
- Sitavig is classified as herpes simplex virus nucleoside analog dna polymerase inhibitor, herpes zoster virus nucleoside analog dna polymerase inhibitor, herpesvirus nucleoside analog dna polymerase inhibitor, per the FDA's Established Pharmacologic Class.
- Is Sitavig FDA-registered?
- Sitavig is on record with the U.S. FDA under application number NDA203791. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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