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Best Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor for herpes genitalis

Top-rated pick: Acyclovir Sodium — pharmaranks score 70/100, the highest of the 3 Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor drugs used for herpes genitalis, ranked by our independent FDA recall-safety score. Compare them with all treatments for herpes genitalis or the full Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor class. Not medical advice — always consult a professional.

Quick answer: Of the 3 herpes simplex virus nucleoside analog dna polymerase inhibitor drugs we rate for herpes genitalis, all are available as lower-cost generics, and most are injectable. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for herpes genitalis; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

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Top herpes simplex virus nucleoside analog dna polymerase inhibitor for herpes genitalis: 1. Acyclovir Sodium · 2. Valtrex · 3. Acyclovir

Best-rated Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor for herpes genitalis, ranked by pharmaranks score
#DrugRatingPharmacy pays
170/100$5View →
270/100$7View →
356/100$5View →

Full ranking · 3 drugs

#1 of 4 in Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor

acyclovir sodium

PrescriptionFDA-sourced

70/100

Acyclovir Sodium is a herpes simplex virus nucleoside analog dna polymerase inhibitor used to treat Chickenpox, Herpes Genitalis, Herpes Labialis, Herpes Zoster Ophthalmicus.

(8 data points)
herpes simplex virus nucleoside analog dna polymerase inhibitorherpes zoster virus nucleoside analog dna polymerase inhibitorherpesvirus nucleoside analog dna polymerase inhibitor

Pharmacy pays

From ~$2.22/30· 6 forms
View details →
#1 of 4 in Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor

valtrex

PrescriptionFDA-sourced

70/100

Valtrex (Valacyclovir Hydrochloride) is a herpes simplex virus nucleoside analog dna polymerase inhibitor used to treat Chickenpox, Herpes Genitalis, Herpes Labialis, Herpes Zoster.

(9 data points)
herpes simplex virus nucleoside analog dna polymerase inhibitorherpes zoster virus nucleoside analog dna polymerase inhibitorherpesvirus nucleoside analog dna polymerase inhibitor

Pharmacy pays

From ~$6.87/30· 2 forms Save up to 31% in class
View details →

acyclovir

PrescriptionFDA-sourced

56/100

Acyclovir is a herpes simplex virus nucleoside analog dna polymerase inhibitor used to treat Chickenpox, Herpes Genitalis, Herpes Labialis, Herpes Zoster Ophthalmicus.

(124 data points)
herpes simplex virus nucleoside analog dna polymerase inhibitorherpes zoster virus nucleoside analog dna polymerase inhibitorherpesvirus nucleoside analog dna polymerase inhibitor

Pharmacy pays

From ~$2.22/30· 6 forms
View details →

Frequently asked

What is the best herpes simplex virus nucleoside analog dna polymerase inhibitor for herpes genitalis?
By our independent recall-safety rating — not an efficacy measure — acyclovir sodium ranks highest among Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor drugs used for herpes genitalis. Always consult a professional.
Which herpes simplex virus nucleoside analog dna polymerase inhibitor drugs treat herpes genitalis?
pharmaranks lists 3 Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor products used for herpes genitalis, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.