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Pharmaranks rates Readyprep Chg 3.2/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Readyprep Chg (Chlorhexidine Gluconate) is a medication used to treat Oral Candidiasis, Periodontal Diseases, Infectious Skin Diseases, Gram-Negative Bacterial Infections.

Chlorhexidine Gluconate · by Medline Industries

Available as a generic: Chlorhexidine Gluconate

64/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
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Key facts

Active ingredient
Chlorhexidine Gluconate
Form
Cloth
Strength
Chlorhexidine Gluconate 2%
Type
Over-the-counter (OTC)
Brand or generic
Brand-name
Manufacturer
Medline Industries
FDA application
NDA207964

What is Readyprep Chg?

From the FDA label:Uses helps reduce bacteria that can potentially cause skin infection for preparation of skin prior to surgery

How to use

Directions use with care in premature infants or infants under 2 months of age. These products may cause irritation or chemical burns. do not microwave product and packaging are not sterile. Follow your hospital policy for skin preparation with non-sterile products. to open package : identify the tear notch labeled on the front of the package. Grasp with both hands on both sides of the tear notch and tear to expose cloth. transfer contents onto prep table, avoiding contact between cloth and outside of package to reduce risk of cloth contamination use [first/a] cloth to prepare the skin area indicated for a moist or dry site, making certain to keep the [second/remaining] cloth[s] where it will not be contaminated. Use [second/additional] cloth to prepare larger areas. dry surgical sites : (such as abdomen or arm): use one cloth to cleanse each 161 cm 2 area (approximately) 5 x 5 inches) of skin to be prepared. Vigorously scrub skin back and forth for 3 minutes, completely wetting treatment area, then discard. Allow area to dry for one (1) minute. Do not rinse. moist surgical sites (such as inguinal fold): use one cloth to cleanse each 65 cm 2 area (approximately 2 x 5 inches) of skin to be prepared. Vigorously scrub skin back and forth for 3 minutes, competely wetting treatment area, then discard. Allow area to dry for one (1) minute. Do not rinse. discard each cloth after a…

Warnings

Important safety information

For external use only Allergy alert: This product may cause a severe allergic reaction. Symptoms may include: wheezing/difficulty breathing shock facial swelling hives rash If an allergic reaction occurs, stop use and seek medical help right away. Do not use on patients allergic to chlorhexidine gluconate or any other ingredient in this product for lumbar punctures or in contact with the meninges on open skin wounds as a general skin cleanser Stop use and ask a doctor if irritation, sensitization, or allergic reaction occurs. These may be signs of a serious condition. When using this product keep out of eyes, ears and mouth. May cause serious or permanent injury if chlorhexidine is permitted to enter and remain. If contact occurs, rinse with cold water right away and contact a doctor. Keep out of reach of children. If swallowed, get medical help or contact a Posion Control Center right away. Allergy alert: This product may cause a severe allergic reaction. Symptoms may include: wheezing/difficulty breathing shock facial swelling hives rash If an allergic reaction occurs, stop use and seek medical help right away.

May treat (source: NIH RxClass)

Dosage forms

Cloth

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Readyprep Chg treat?
Readyprep Chg (Chlorhexidine Gluconate) may be used to treat oral candidiasis, periodontal diseases, infectious skin diseases, gram-negative bacterial infections, gram-positive bacterial infections, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How is Readyprep Chg rated?
pharmaranks gives Readyprep Chg a composite score of 3.2 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Readyprep Chg?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Readyprep Chg. To pay less, look for a store-brand version with the same active ingredient (Chlorhexidine Gluconate), which is typically cheaper, and compare unit prices. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Readyprep Chg?
Readyprep Chg is marketed by Medline Industries. You can see Medline Industries's full profile, rating, and other products on pharmaranks.
Is Readyprep Chg a brand-name or generic drug?
Readyprep Chg is a brand-name product with the active ingredient Chlorhexidine Gluconate. Lower-cost generic equivalents containing Chlorhexidine Gluconate are available — ask your pharmacist.
Is Readyprep Chg available over the counter?
Yes. Readyprep Chg is an over-the-counter (OTC) product — you can buy it without a prescription. Follow the label directions and ask a pharmacist if you're unsure whether it's right for you.
What forms does Readyprep Chg come in?
Readyprep Chg is currently marketed as cloth, per the FDA's National Drug Code Directory.
Is Readyprep Chg FDA-registered?
Readyprep Chg is on record with the U.S. FDA under application number NDA207964. You can verify this on its official FDA label.
Has Readyprep Chg been recalled by the FDA?
Yes. Readyprep Chg has 1 recorded FDA recall event in the openFDA enforcement database. A recall removes specific lots from the market — usually for manufacturing, contamination, potency, or labeling issues — and does not mean the drug is unsafe to take; your specific lot was almost certainly never affected. This recall history is factored into its safety score above. Always check the FDA recall database or your pharmacist for current alerts.
Is Readyprep Chg safe?
There's no single safe-or-not verdict. pharmaranks gives Readyprep Chg a recall-safety score of 64/100, based on its FDA recall history (1 recorded recall event) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about CHLORHEXIDINE GLUCONATE

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 9,577 reports naming CHLORHEXIDINE GLUCONATE — the active ingredient in Readyprep Chg, and the FDA flagged 86% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • fatigue2,599 reports
  • rash2,443 reports
  • joint swelling2,392 reports
  • hypersensitivity2,276 reports
  • impaired healing2,267 reports
  • folliculitis2,259 reports
  • weight increased2,252 reports
  • stomatitis2,239 reports

Read these as a signal, not a rate. A report does not mean CHLORHEXIDINE GLUCONATE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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