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Best treatments for periodontal diseases

8 products may treat periodontal diseases. The current highest-rated option is chg scrub. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 8 drugs we list for periodontal diseases, none are yet flagged as generics in our price data. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for periodontal diseases — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Top-rated picks for periodontal diseases: 1. Chg Scrub · 2. Chlorhexidine Gluconate · 3. Cida-Stat

Top-rated treatments for periodontal diseases, ranked by pharmaranks score
#DrugRatingPharmacy pays
170/100View →
270/100View →
370/100View →
466/100View →
5Not yet ratedView →
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Full ranking · 8 treatments

chg scrub

Over-the-counterFDA-sourced

70/100

Chg Scrub (Chlorhexidine Gluconate) is a medication used to treat Oral Candidiasis, Periodontal Diseases, Infectious Skin Diseases, Gram-Negative Bacterial Infections.

(5 data points)
candidiasis, oralperiodontal diseasesskin diseases, infectious
Available online
View details →
BECTON DICKINSON CO logo

chlorhexidine gluconate

Over-the-counterFDA-sourced

70/100

Chlorhexidine Gluconate is a medication used to treat Oral Candidiasis, Periodontal Diseases, Infectious Skin Diseases, Gram-Negative Bacterial Infections.

(1 data points)
candidiasis, oralperiodontal diseasesskin diseases, infectious
Available online
View details →

cida-stat

Over-the-counterFDA-sourced

70/100

Cida-Stat (Chlorhexidine Gluconate) is a medication used to treat Oral Candidiasis, Periodontal Diseases, Infectious Skin Diseases, Gram-Negative Bacterial Infections.

(5 data points)
candidiasis, oralperiodontal diseasesskin diseases, infectious
Available online
View details →
MEDLINE INDUSTRIES logo

readyprep chg

Over-the-counterFDA-sourced

66/100

Readyprep Chg (Chlorhexidine Gluconate) is a medication used to treat Oral Candidiasis, Periodontal Diseases, Infectious Skin Diseases, Gram-Negative Bacterial Infections.

(38 data points)
candidiasis, oralperiodontal diseasesskin diseases, infectious
Available online
View details →

bioscrub

Over-the-counterFDA-sourced

New

Bioscrub (Chlorhexidine Gluconate) is a medication used to treat Oral Candidiasis, Periodontal Diseases, Infectious Skin Diseases, Gram-Negative Bacterial Infections.

candidiasis, oralperiodontal diseasesskin diseases, infectious
Available online
View details →

dyna-hex 2

Over-the-counterFDA-sourced

New

Dyna-Hex 2 (Chlorhexidine Gluconate) is a medication used to treat Oral Candidiasis, Periodontal Diseases, Infectious Skin Diseases, Gram-Negative Bacterial Infections.

candidiasis, oralperiodontal diseasesskin diseases, infectious
Available online
View details →

Frequently asked

What treats periodontal diseases?
Our catalog lists 8 products that may treat periodontal diseases, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is chg scrub.
What is the best-rated treatment for periodontal diseases?
By our independent recall-safety rating — not an efficacy measure — chg scrub ranks highest among the products we list for periodontal diseases. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.