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prozac weekly

Prozac Weekly (Fluoxetine Hydrochloride) is a serotonin reuptake inhibitor used to treat Bulimia, Major Depressive Disorder, Obsessive-Compulsive Disorder, Panic Disorder.

Fluoxetine Hydrochloride · by Lilly

Available as a generic: Fluoxetine Hydrochloride

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Fluoxetine Hydrochloride
Form
Capsule, Oral pellets
Strength
Fluoxetine Hydrochloride EQ 90MG Base **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Lilly
Half-life
about 1 to 3 days (roughly 24-72 hours) after a single dose, lengthening to about 4 to 6 days with ongoing daily use (how long it stays in your system)
What the pharmacy pays
~$0.05 per ml — not your price
FDA application
NDA021235
Availability
Discontinued (per FDA)

How long does Fluoxetine Hydrochloride stay in your body?

The elimination half-life of fluoxetine hydrochloride is about 1 to 3 days (roughly 24-72 hours) after a single dose, lengthening to about 4 to 6 days with ongoing daily use — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Fluoxetine's active metabolite norfluoxetine has a much longer elimination half-life of about 4 to 16 days, so the drug clears from the body very slowly (over weeks); half-lives are also longer in people with liver cirrhosis (fluoxetine roughly 7-8 days vs 2-3 days normally).

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: PROZAC- fluoxetine hydrochloride capsule (DailyMed).

Drug class

How this class works, per Selective Serotonin Reuptake Inhibitors - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Prozac Weekly ranks — best-rated serotonin reuptake inhibitor for:

Dosage forms

Capsule and Oral pellets

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Prozac Weekly treat?
Prozac Weekly (Fluoxetine Hydrochloride) may be used to treat bulimia, major depressive disorder, obsessive-compulsive disorder, panic disorder, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Prozac Weekly work?
Prozac Weekly is a serotonin reuptake inhibitor. Selective serotonin reuptake inhibitors (SSRIs) block the transporter that pulls serotonin back into nerve cells, so more of this mood-related chemical stays in the gaps between neurons to keep signaling. They act mainly on serotonin, which tends to mean fewer side effects than older antidepressants.
How much does Prozac Weekly cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.05 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Prozac Weekly?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Prozac Weekly. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Prozac Weekly?
Prozac Weekly is marketed by Lilly. You can see Lilly's full profile, rating, and other products on pharmaranks.
Is Prozac Weekly a brand-name or generic drug?
Prozac Weekly is a brand-name product with the active ingredient Fluoxetine Hydrochloride. Lower-cost generic equivalents containing Fluoxetine Hydrochloride are available — ask your pharmacist.
Is Prozac Weekly available over the counter?
No. Prozac Weekly is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Prozac Weekly come in?
Prozac Weekly is currently marketed as capsule and oral pellets, per the FDA's National Drug Code Directory.
What class of drug is Prozac Weekly?
Prozac Weekly is classified as serotonin reuptake inhibitor, per the FDA's Established Pharmacologic Class.
Is Prozac Weekly FDA-registered?
Prozac Weekly is on record with the U.S. FDA under application number NDA021235. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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