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onsolis

Onsolis (Fentanyl Citrate) is an opioid agonist used to treat Pain.

Fentanyl Citrate · by Adalvo

Available as a generic: Fentanyl Citrate

⚠ FDA reports a current shortage of the injection form — availability differs between suppliers — see drug shortages →
Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
Lower-cost optionsSave up to 99%
This medication~$9.51
Cheapest in class · imodium a-d~$0.05
See FDA-approved alternatives

Key facts

Active ingredient
Fentanyl Citrate
Drug class
Opioid Agonist
Form
Film
Strength
Fentanyl Citrate EQ 0.2MG Base · Fentanyl Citrate EQ 0.4MG Base · Fentanyl Citrate EQ 0.6MG Base · Fentanyl Citrate EQ 0.8MG Base · Fentanyl Citrate EQ 1.2MG Base
Type
Prescription (Rx)
Brand or generic
Brand-name
May treat
pain
Manufacturer
Adalvo
What the pharmacy pays
~$9.51 per ml — not your price
FDA application
NDA022266
Availability
Discontinued (per FDA)

Drug class

How this class works, per Mu Receptors - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Onsolis ranks — best-rated opioid agonist for:

Dosage forms

Film

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Onsolis treat?
Onsolis (Fentanyl Citrate) may be used to treat pain, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Onsolis work?
Onsolis is a opioid agonist. Opioid agonists bind opioid receptors (mainly mu receptors) on nerves in the brain and spinal cord, dampening the release of pain-signaling chemicals so fewer pain messages reach the brain, which relieves moderate to severe pain.
How much does Onsolis cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $9.51 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Imodium A-D — about $0.05 on the same basis.
Is there a coupon or discount for Onsolis?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Onsolis. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Onsolis?
Onsolis is marketed by Adalvo. You can see Adalvo's full profile, rating, and other products on pharmaranks.
Is Onsolis a brand-name or generic drug?
Onsolis is a brand-name product with the active ingredient Fentanyl Citrate. Lower-cost generic equivalents containing Fentanyl Citrate are available — ask your pharmacist.
Is Onsolis available over the counter?
No. Onsolis is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Onsolis come in?
Onsolis is currently marketed as film, per the FDA's National Drug Code Directory.
What class of drug is Onsolis?
Onsolis is classified as opioid agonist, per the FDA's Established Pharmacologic Class.
Is Onsolis FDA-registered?
Onsolis is on record with the U.S. FDA under application number NDA022266. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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