normodyne

How long does Labetalol Hydrochloride stay in your body?

The elimination half-life of labetalol hydrochloride is about 6 to 8 hours after an oral dose (about 5.5 hours after an intravenous dose) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The FDA label gives two numbers depending on route: roughly 6 to 8 hours after an oral dose and about 5.5 hours after IV infusion. The label states that in people with reduced liver or kidney function the elimination half-life of labetalol is NOT changed — but in liver impairment more of an oral dose reaches the bloodstream, because less of it is broken down on first pass through the liver, so the same dose produces higher levels. Labetalol is cleared mainly by conjugation to glucuronide metabolites, excreted in urine and bile; the label describes no active metabolite that outlasts the parent drug. Neither hemodialysis nor peritoneal dialysis removes a meaningful amount (less than 1%). There is no extended-release labetalol marketed in the US — only immediate-release tablets and the injection.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Labetalol Hydrochloride Injection — FDA prescribing information, Clinical Pharmacology (DailyMed).

Frequently asked questions

What does Normodyne treat?

Normodyne (Labetalol Hydrochloride) may be used to treat angina pectoris, heart failure, malignant hypertension, myocardial infarction, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How does Normodyne work?

Normodyne is a beta-adrenergic blocker. Beta-blockers block adrenaline (epinephrine) and noradrenaline from acting on beta-adrenergic receptors, mainly in the heart. This slows the heart rate, reduces how forcefully the heart contracts, and lowers blood pressure, easing the workload on the heart.

How much does Normodyne cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $4.36 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Atenolol — about $0.76 on the same basis.

Is there a coupon or discount for Normodyne?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Normodyne. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Normodyne?

Normodyne is marketed by Schering. You can see Schering's full profile, rating, and other products on pharmaranks.

Is Normodyne a brand-name or generic drug?

Normodyne is a brand-name product with the active ingredient Labetalol Hydrochloride.

Is Normodyne available over the counter?

No. Normodyne is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Normodyne come in?

Normodyne is currently marketed as tablet, per the FDA's National Drug Code Directory.

What class of drug is Normodyne?

Normodyne is classified as beta-adrenergic blocker, per the FDA's Established Pharmacologic Class.

Is Normodyne FDA-registered?

Normodyne is on record with the U.S. FDA under application number NDA018686. You can verify this on its official FDA label.