
jakafi
Jakafi (Ruxolitinib Phosphate) is a janus kinase inhibitor used to treat Polycythemia Vera, Primary Myelofibrosis.
Ruxolitinib Phosphate · by Incyte Corp
Key facts
- Active ingredient
- Ruxolitinib Phosphate
- Drug class
- Janus Kinase Inhibitor
- Form
- Tablet
- Strength
- Ruxolitinib Phosphate EQ 10MG Base · Ruxolitinib Phosphate EQ 15MG Base · Ruxolitinib Phosphate EQ 20MG Base · Ruxolitinib Phosphate EQ 25MG Base · Ruxolitinib Phosphate EQ 5MG Base
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- polycythemia vera, primary myelofibrosis
- Manufacturer
- Incyte Corp
- FDA application
- NDA202192
Drug class
How this class works, per Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach - PMC, NCBI.
May treat (source: NIH RxClass)
See how Jakafi ranks — best-rated janus kinase inhibitor for:
Dosage forms
Tablet
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Jakafi treat?
- Jakafi (Ruxolitinib Phosphate) may be used to treat polycythemia vera, primary myelofibrosis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Jakafi work?
- Jakafi is a janus kinase inhibitor. JAK inhibitors block Janus kinase enzymes inside immune cells. These enzymes normally pass along messages from inflammatory signals (cytokines) to relay proteins that switch on genes, so blocking them turns down the overactive immune signaling that drives diseases like rheumatoid arthritis.
- Is there a coupon or discount for Jakafi?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Jakafi. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Jakafi?
- Jakafi is marketed by Incyte Corp. You can see Incyte Corp's full profile, rating, and other products on pharmaranks.
- Is Jakafi a brand-name or generic drug?
- Jakafi is a brand-name product with the active ingredient Ruxolitinib Phosphate.
- Is Jakafi available over the counter?
- No. Jakafi is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Jakafi come in?
- Jakafi is currently marketed as tablet, per the FDA's National Drug Code Directory.
- What class of drug is Jakafi?
- Jakafi is classified as janus kinase inhibitor, kinase inhibitor, per the FDA's Established Pharmacologic Class.
- Is Jakafi FDA-registered?
- Jakafi is on record with the U.S. FDA under application number NDA202192. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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