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estradiol cypionate

Estradiol Cypionate is a medication used to treat Breast Neoplasms, Hypogonadism, Premature Menopause, Menorrhagia.

Generic · by Quad Pharms

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Estradiol Cypionate
Form
Injectable
Strength
Estradiol Cypionate 5MG/ML
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Quad Pharms
FDA application
ANDA089310
Availability
Discontinued (per FDA)

May treat (source: NIH RxClass)

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

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Request a 90-day supply

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Use copay cards

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Frequently asked questions

What does Estradiol Cypionate treat?
Estradiol Cypionate (Estradiol Cypionate) may be used to treat breast neoplasms, hypogonadism, premature menopause, menorrhagia, prostatic neoplasms, primary ovarian insufficiency, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
Is there a coupon or discount for Estradiol Cypionate?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Estradiol Cypionate. To pay less, Estradiol Cypionate is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Estradiol Cypionate?
Estradiol Cypionate is marketed by Quad Pharms. You can see Quad Pharms's full profile, rating, and other products on pharmaranks.
Is Estradiol Cypionate a brand-name or generic drug?
Estradiol Cypionate is a generic medication; its active ingredient is Estradiol Cypionate. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Estradiol Cypionate available over the counter?
No. Estradiol Cypionate is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Estradiol Cypionate come in?
Estradiol Cypionate is currently marketed as injectable, per the FDA's National Drug Code Directory.
Is Estradiol Cypionate FDA-registered?
Estradiol Cypionate is on record with the U.S. FDA under application number ANDA089310. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about Estradiol Cypionate

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 81,226 reports naming Estradiol Cypionate, and the FDA flagged 51% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • product adhesion issue8,308 reports
  • fatigue6,370 reports
  • headache5,420 reports
  • nausea5,319 reports
  • dyspnoea4,641 reports
  • rash4,525 reports
  • pruritus4,446 reports
  • arthralgia4,427 reports

Read these as a signal, not a rate. A report does not mean Estradiol Cypionate caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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