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duraprep

Duraprep is a combination medicine containing Iodine Povacrylex and Isopropyl Alcohol.

Iodine Povacrylex and Isopropyl Alcohol · by Solventum

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
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Key facts

Active ingredient
Iodine Povacrylex and Isopropyl Alcohol
Form
Solution
Strength
Iodine Povacrylex EQ 0.7% Iodine; Isopropyl Alcohol 74% (26ML) · Iodine Povacrylex EQ 0.7% Iodine; Isopropyl Alcohol 74% (6ML)
Type
Over-the-counter (OTC)
Brand or generic
Brand-name
Manufacturer
Solventum
FDA application
NDA021586

What is Duraprep?

From the FDA label:Uses patient preoperative skin preparation: for preparation of the skin prior to surgery helps reduce bacteria that potentially can cause skin infection

How to use

Directions (follow all directions for use) at the end of the prep, discard any portion of the solution which is not required to cover the prep area. It is not necessary to use the entire amount available. Getting Patient Ready for Solution: use in well-ventilated area do not microwave or heat the solution applicator apply to clean, completely dry, residue-free, intact skin when hair removal is necessary, use a surgical clipper on the morning of the surgery. If a wet shave is used, thoroughly remove all soap residues. Activating the Applicator: grasp product by wrapping hand and fingers around the labeled portion of the applicator. Place thumb on the lever. with sponge face parallel to the floor, snap lever. Allow all fluid to flow into sponge. When Applying Solution: DO NOT SCRUB . Paint a single, uniform application and do not reprep area. do not allow solution to pool . Use sponge applicator to absorb excess solution and continue to apply a uniform coating. If solution accidentally gets outside of prep area, remove excess with gauze. tuck prep towels as needed under both sides of the neck to absorb excess solution. Remove towels before draping. avoid getting solution into hairy areas. Wet hair is flammable . Hair may take up to 1 hour to dry. when prepping skin folds, toes, or fingers, use a sterile-gloved hand to hold skin apart until completely dry. Otherwise, skin may…

Warnings

Important safety information

For external use only. Flammable, keep away from fire or flame. To reduce the risk of fire, PREP CAREFULLY: solution contains alcohol and gives off flammable vapors do not drape or use ignition source (e.g., cautery, laser) until solution is completely dry (minimum of 3 minutes on hairless skin; up to 1 hour in hair). avoid getting solution into hairy areas. Wet hair is flammable . Hair may take up to 1 hour to dry. do not allow solution to pool remove solution-stained material from prep area Do not use on patients with known allergies to iodine or any other ingredients in this product on open wounds, on mucous membranes, or as a general skin cleanser in infants less than 2 months old due to the risk of excessive skin irritation and transient hypothyroidism When using this product keep out of eyes, ears, and mouth. May cause serious injury if permitted to enter and remain. If contact occurs, flush with cold water right away and contact a doctor. to avoid skin injury, care should be taken when removing drapes, tapes, etc…applied over film use with caution in women who are breast-feeding due to the potential for transient hypothyroidism in the nursing newborn Stop use and ask a doctor if irritation, sensitization or allergic reaction occurs. These may be signs of a serious condition. On rare occasions, use of this product has been associated with skin blistering. Keep out of reach of children . If swallowed, get medical help or contact a Poison Control Center right away.

Dosage forms

Solution

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

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Frequently asked questions

Is there a coupon or discount for Duraprep?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Duraprep. To pay less, look for a store-brand version with the same active ingredient (Iodine Povacrylex and Isopropyl Alcohol), which is typically cheaper, and compare unit prices. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Duraprep?
Duraprep is marketed by Solventum. You can see Solventum's full profile, rating, and other products on pharmaranks.
Is Duraprep a brand-name or generic drug?
Duraprep is a brand-name product with the active ingredient Iodine Povacrylex and Isopropyl Alcohol.
Is Duraprep available over the counter?
Yes. Duraprep is an over-the-counter (OTC) product — you can buy it without a prescription. Follow the label directions and ask a pharmacist if you're unsure whether it's right for you.
What forms does Duraprep come in?
Duraprep is currently marketed as solution, per the FDA's National Drug Code Directory.
Is Duraprep FDA-registered?
Duraprep is on record with the U.S. FDA under application number NDA021586. You can verify this on its official FDA label.
Is Duraprep safe?
There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Duraprep. Review its FDA-label side effects and warnings below, and always consult a licensed professional.

Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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