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ADVIL ALLERGY SINUS vs DURAPREP

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

72/100
New

Pharmacy pays

Type

OTC
OTC

Active ingredient

CHLORPHENIRAMINE MALEATE AND IBUPROFEN AND PSEUDOEPHEDRINE HYDROCHLORIDE
IODINE POVACRYLEX AND ISOPROPYL ALCOHOL

Dosage forms

Tablet
Solution

Drug class

Boxed warning

None
None

Half-life

roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Advil Allergy Sinus and Duraprep?

Advil Allergy Sinus contains Chlorpheniramine Maleate and Ibuprofen and Pseudoephedrine Hydrochloride, while Duraprep contains Iodine Povacrylex and Isopropyl Alcohol — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.