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diulo

Diulo (Metolazone) is a thiazide-like diuretic used to treat Edema, Heart Failure, Hypertension, Nephrotic Syndrome.

Metolazone · by Gd Searle LLC

Available as a generic: Metolazone

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
~$8.76 /30
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Lower-cost optionsSave up to 70%
This medication~$8.76/30
Cheapest in class · hemiclor~$2.67/30
See FDA-approved alternatives

Key facts

Active ingredient
Metolazone
Form
Tablet
Strength
Metolazone 10MG · Metolazone 2.5MG · Metolazone 5MG
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Gd Searle LLC
What the pharmacy pays
~$8.76 for 30 — not your price
FDA application
NDA018535
Availability
Discontinued (per FDA)

Drug class

May treat (source: NIH RxClass)

See how Diulo ranks — best-rated thiazide-like diuretic for:

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Diulo treat?
Diulo (Metolazone) may be used to treat edema, heart failure, hypertension, nephrotic syndrome, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How much does Diulo cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $8.76 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Hemiclor — about $2.67 on the same basis.
Is there a coupon or discount for Diulo?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Diulo. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Diulo?
Diulo is marketed by Gd Searle LLC. You can see Gd Searle LLC's full profile, rating, and other products on pharmaranks.
Is Diulo a brand-name or generic drug?
Diulo is a brand-name product with the active ingredient Metolazone. Lower-cost generic equivalents containing Metolazone are available — ask your pharmacist.
Is Diulo available over the counter?
No. Diulo is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Diulo come in?
Diulo is currently marketed as tablet, per the FDA's National Drug Code Directory.
What class of drug is Diulo?
Diulo is classified as thiazide-like diuretic, per the FDA's Established Pharmacologic Class.
Is Diulo FDA-registered?
Diulo is on record with the U.S. FDA under application number NDA018535. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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