Skip to content
ppharmaranks
Menu

dexmedetomidine hydrochloride

Pharmaranks rates Dexmedetomidine Hydrochloride 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Dexmedetomidine Hydrochloride is a central alpha-2 adrenergic agonist used to treat Pain, Psychomotor Agitation.

Central Alpha-2 Adrenergic Agonist · by Rising

Generic of Precedex

⚠ FDA reports a current shortage of the injection form — availability differs between suppliers — see drug shortages →
72/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Form
Injectable, Solution
Strength
Dexmedetomidine Hydrochloride EQ 200MCG BASE/2ML (EQ 100MCG BASE/ML)
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Rising
FDA application
ANDA202585

Drug class

How this class works, per Clonidine - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Dexmedetomidine Hydrochloride ranks — best-rated central alpha-2 adrenergic agonist for:

Dosage forms

Injectable and Solution

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Dexmedetomidine Hydrochloride treat?
Dexmedetomidine Hydrochloride (Dexmedetomidine Hydrochloride) may be used to treat pain, psychomotor agitation, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Dexmedetomidine Hydrochloride work?
Dexmedetomidine Hydrochloride is a central alpha-2 adrenergic agonist. These drugs activate alpha-2 receptors in the brainstem, which tells the nervous system to send out less norepinephrine and reduce sympathetic (fight-or-flight) signaling to the body. With less of this stimulation, blood vessels relax and heart rate slows, lowering blood pressure.
How is Dexmedetomidine Hydrochloride rated?
pharmaranks gives Dexmedetomidine Hydrochloride a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Dexmedetomidine Hydrochloride?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Dexmedetomidine Hydrochloride. To pay less, Dexmedetomidine Hydrochloride is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Dexmedetomidine Hydrochloride?
Dexmedetomidine Hydrochloride is marketed by Rising. You can see Rising's full profile, rating, and other products on pharmaranks.
Is Dexmedetomidine Hydrochloride a brand-name or generic drug?
Dexmedetomidine Hydrochloride is a generic medication; its active ingredient is Dexmedetomidine Hydrochloride. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Dexmedetomidine Hydrochloride available over the counter?
No. Dexmedetomidine Hydrochloride is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Dexmedetomidine Hydrochloride come in?
Dexmedetomidine Hydrochloride is currently marketed as injectable and solution, per the FDA's National Drug Code Directory.
What class of drug is Dexmedetomidine Hydrochloride?
Dexmedetomidine Hydrochloride is classified as central alpha-2 adrenergic agonist, per the FDA's Established Pharmacologic Class.
Is Dexmedetomidine Hydrochloride FDA-registered?
Dexmedetomidine Hydrochloride is on record with the U.S. FDA under application number ANDA202585. You can verify this on its official FDA label.
Has Dexmedetomidine Hydrochloride been recalled by the FDA?
Dexmedetomidine Hydrochloride has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Dexmedetomidine Hydrochloride safe?
There's no single safe-or-not verdict. pharmaranks gives Dexmedetomidine Hydrochloride a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about Dexmedetomidine Hydrochloride

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 1,864 reports naming Dexmedetomidine Hydrochloride, and the FDA flagged 97% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • bradycardia190 reports
  • hypotension98 reports
  • product administered to patient of inappropriate age72 reports
  • pyrexia72 reports
  • oxygen saturation decreased59 reports
  • diabetes insipidus57 reports
  • agitation52 reports
  • arteriospasm coronary50 reports

Read these as a signal, not a rate. A report does not mean Dexmedetomidine Hydrochloride caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

Reviews

No reviews yet. Be the first to write one.

Write a review

Reviews are user opinions, not medical advice. Consult a licensed professional.

People also viewed

Compare Dexmedetomidine Hydrochloride head-to-head

More central alpha-2 adrenergic agonist drugs

Identify a pill by its imprint →Check a drug interaction →Drug recalls →

Browse medications A–Z

Research products from A to Z, compare independent ratings, and find alternatives.

dexmedetomidine hydrochloride

72/100