Best treatments for psychomotor agitation
6 products may treat psychomotor agitation, spanning FDA drug classes such as central alpha-2 adrenergic agonist, benzodiazepine, general anesthetic. The current highest-rated option is dexmedetomidine hydrochloride. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.
Quick answer: Of the 6 drugs we list for psychomotor agitation, 3 are available as lower-cost generics, spanning classes such as central alpha-2 adrenergic agonist, benzodiazepine, general anesthetic. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for psychomotor agitation — so confirm the right choice with your prescriber.
Top-rated picks for psychomotor agitation: 1. Dexmedetomidine Hydrochloride · 2. Nayzilam · 3. Diprivan
| # | Drug | Rating | Type | Form | Class | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|---|
| 1 | 72/100 | Prescription | Injectable | Central alpha-2 Adrenergic Agonist | No data | — | View → | |
| 2 | 70/100 | Prescription | Spray/Inhaler | Benzodiazepine | Generic | $0 | View → | |
| 3 | 64/100 | Prescription | Injectable | General Anesthetic | Generic | $0 | View → | |
| 4 | 64/100 | Prescription | Injectable | Benzodiazepine | Generic | $0 | View → | |
| 5 | 60/100 | Prescription | Injectable | Central alpha-2 Adrenergic Agonist | No data | — | View → | |
| 6 | Not yet rated | Prescription | Film | Central alpha-2 Adrenergic Agonist | No data | — | View → |
Narrow by drug class
Explore the class hubs: central alpha-2 adrenergic agonist · benzodiazepine
Full ranking · 6 treatments
dexmedetomidine hydrochloride
PrescriptionFDA-sourced
Dexmedetomidine Hydrochloride is a central alpha-2 adrenergic agonist used to treat Pain, Psychomotor Agitation.
Price varies
nayzilam
Boxed warningPrescriptionFDA-sourced
Nayzilam (Midazolam) is a benzodiazepine used to treat Anxiety Disorders, Psychomotor Agitation, Status Epilepticus.
Pharmacy pays
From ~$0.23· 5 formsdiprivan
PrescriptionFDA-sourced
Diprivan (Propofol) is a general anesthetic used to treat Delirium, Pain, Psychomotor Agitation, Status Epilepticus.
Pharmacy pays
$0.17 /mL
midazolam hydrochloride
Boxed warningPrescriptionFDA-sourced
Midazolam Hydrochloride is a benzodiazepine used to treat Anxiety Disorders, Psychomotor Agitation, Status Epilepticus.
Pharmacy pays
From ~$0.23· 5 formsprecedex
PrescriptionFDA-sourced
Precedex (Dexmedetomidine Hydrochloride) is a central alpha-2 adrenergic agonist used to treat Pain, Psychomotor Agitation.
Price varies
igalmi
PrescriptionFDA-sourced
Igalmi (Dexmedetomidine Hydrochloride) is a central alpha-2 adrenergic agonist used to treat Pain, Psychomotor Agitation.
Price varies
Frequently asked
- What treats psychomotor agitation?
- Our catalog lists 6 products that may treat psychomotor agitation, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is dexmedetomidine hydrochloride.
- What is the best-rated treatment for psychomotor agitation?
- By our independent recall-safety rating — not an efficacy measure — dexmedetomidine hydrochloride ranks highest among the products we list for psychomotor agitation. Always consult a professional.
- How are these treatments ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
- What types of drugs treat psychomotor agitation?
- Treatments for psychomotor agitation span FDA drug classes including central alpha-2 adrenergic agonist, benzodiazepine, general anesthetic. Compare every option side by side, ranked by independent rating, above.
Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.