cloderm
Cloderm (Clocortolone Pivalate) is a corticosteroid used to treat Facial Dermatoses, Foot Dermatoses, Hand Dermatoses, Inflammation.
Clocortolone Pivalate · by Legacy Pharma
Available as a generic: Clocortolone Pivalate
Key facts
- Active ingredient
- Clocortolone Pivalate
- Drug class
- Corticosteroid
- Form
- Topical
- Strength
- Clocortolone Pivalate 0.1%
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- facial dermatoses, foot dermatoses, hand dermatoses
- Manufacturer
- Legacy Pharma
- What the pharmacy pays
- ~$5.21 per gm — not your price
- FDA application
- NDA017765
Drug class
How this class works, per Corticosteroids - StatPearls - NCBI Bookshelf.
May treat (source: NIH RxClass)
See how Cloderm ranks — best-rated corticosteroid for:
Dosage forms
Topical
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Cloderm treat?
- Cloderm (Clocortolone Pivalate) may be used to treat facial dermatoses, foot dermatoses, hand dermatoses, inflammation, leg dermatoses, scalp dermatoses, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Cloderm work?
- Cloderm is a corticosteroid. Corticosteroids mimic the body's natural stress hormone cortisol: they enter cells and bind a glucocorticoid receptor that switches off genes for inflammatory chemicals, calming swelling, redness, and an overactive immune response.
- How much does Cloderm cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $5.21 per gm, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Cortenema — about $0.14 on the same basis.
- Is there a coupon or discount for Cloderm?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Cloderm. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Cloderm?
- Cloderm is marketed by Legacy Pharma. You can see Legacy Pharma's full profile, rating, and other products on pharmaranks.
- Is Cloderm a brand-name or generic drug?
- Cloderm is a brand-name product with the active ingredient Clocortolone Pivalate. Lower-cost generic equivalents containing Clocortolone Pivalate are available — ask your pharmacist.
- Is Cloderm available over the counter?
- No. Cloderm is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Cloderm come in?
- Cloderm is currently marketed as topical, per the FDA's National Drug Code Directory.
- What class of drug is Cloderm?
- Cloderm is classified as corticosteroid, per the FDA's Established Pharmacologic Class.
- Is Cloderm FDA-registered?
- Cloderm is on record with the U.S. FDA under application number NDA017765. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about CLOCORTOLONE PIVALATE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 39 reports naming CLOCORTOLONE PIVALATE — the active ingredient in Cloderm, and the FDA flagged 36% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- rash7 reports
- pruritus5 reports
- skin exfoliation4 reports
- cardiac disorder3 reports
- dermatitis atopic3 reports
- eczema3 reports
- erythema3 reports
- headache3 reports
Read these as a signal, not a rate. A report does not mean CLOCORTOLONE PIVALATE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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