chlorthalidone

How long does Chlorthalidone stay in your body?

The elimination half-life of chlorthalidone is about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is an older-format label (CLINICAL PHARMACOLOGY, not a PLR §12.3), and it gives its numbers in two ways: a mean half-life of 40 hours across the 50–200 mg dose range, and dose-specific elimination half-lives of 53 hours (50 mg) and 60 hours (100 mg). Only one phase is described, so the figures above are the elimination values the label states — it does not report a separate distribution phase. No active metabolite is described: the label says chlorthalidone is largely excreted unchanged by the kidneys and that data on metabolites and non-renal elimination routes "have yet to be clarified." It is not a prodrug. Do not confuse the half-life with the duration of diuretic effect — the label describes diuresis beginning in about 2.6 hours and continuing up to 72 hours, which is a different measure. The label does NOT quantify how the half-life changes with age, kidney impairment, or liver impairment; it gives no geriatric or renal/hepatic pharmacokinetic numbers. It does warn that cumulative effects of the drug may develop in patients with impaired renal function, and to use caution in severe renal disease and in impaired hepatic function — but it does not state a half-life for those groups, so no number should be inferred for them.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: DailyMed — CHLORTHALIDONE tablet (Clinical Pharmacology).

Frequently asked questions

What does Chlorthalidone treat?

Chlorthalidone (Chlorthalidone) may be used to treat edema, glomerulonephritis, heart failure, hypertension, liver cirrhosis, nephrotic syndrome, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How much does Chlorthalidone cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $2.67 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Chlorthalidone?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Chlorthalidone. To pay less, Chlorthalidone is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Chlorthalidone?

Chlorthalidone is marketed by Ivax Pharms. You can see Ivax Pharms's full profile, rating, and other products on pharmaranks.

Is Chlorthalidone a brand-name or generic drug?

Chlorthalidone is a generic medication; its active ingredient is Chlorthalidone. Generics contain the same active ingredient as the brand-name original and are usually lower cost.

Is Chlorthalidone available over the counter?

No. Chlorthalidone is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Chlorthalidone come in?

Chlorthalidone is currently marketed as tablet, per the FDA's National Drug Code Directory.

What class of drug is Chlorthalidone?

Chlorthalidone is classified as thiazide-like diuretic, per the FDA's Established Pharmacologic Class.

Is Chlorthalidone FDA-registered?

Chlorthalidone is on record with the U.S. FDA under application number ANDA087176. You can verify this on its official FDA label.