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Pharmaranks rates Astepro 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Astepro (Azelastine Hydrochloride) is a histamine-1 receptor antagonist used to treat Allergic Conjunctivitis, Perennial Allergic Rhinitis, Vasomotor Rhinitis.

Azelastine Hydrochloride · by Viatris

Available as a generic: Azelastine Hydrochloride

70/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
$0.58 /mL
Compare online visit pricesWe may earn a commission · never affects ratings
Lower-cost optionsSave up to 89%
This medication~$0.58
Cheapest in class · children's cetirizine hydrochloride allergy~$0.06
See FDA-approved alternatives

Key facts

Active ingredient
Azelastine Hydrochloride
Form
Spray/Inhaler, metered
Strength
Azelastine Hydrochloride 0.137MG/SPRAY **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Azelastine Hydrochloride 0.2055MG/SPRAY
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Viatris
What the pharmacy pays
~$0.58 per ml — not your price
FDA application
NDA022203
Availability
Discontinued (per FDA)

Drug class

How this class works, per Antihistamines - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Astepro ranks — best-rated histamine-1 receptor antagonist for:

Dosage forms

Spray/Inhaler, metered

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Astepro treat?
Astepro (Azelastine Hydrochloride) may be used to treat allergic conjunctivitis, perennial allergic rhinitis, vasomotor rhinitis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Astepro work?
Astepro is a histamine-1 receptor antagonist. H1 antihistamines work by blocking histamine, the chemical released during an allergic reaction, from attaching to H1 receptors. This prevents the sneezing, itching, runny nose, watery eyes, and hives that histamine would otherwise trigger.
How is Astepro rated?
pharmaranks gives Astepro a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Astepro cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.58 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Children's Cetirizine Hydrochloride Allergy — about $0.06 on the same basis.
Is there a coupon or discount for Astepro?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Astepro. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Astepro?
Astepro is marketed by Viatris. You can see Viatris's full profile, rating, and other products on pharmaranks.
Is Astepro a brand-name or generic drug?
Astepro is a brand-name product with the active ingredient Azelastine Hydrochloride. Lower-cost generic equivalents containing Azelastine Hydrochloride are available — ask your pharmacist.
Is Astepro available over the counter?
No. Astepro is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Astepro come in?
Astepro is currently marketed as spray/inhaler, metered, per the FDA's National Drug Code Directory.
What class of drug is Astepro?
Astepro is classified as histamine-1 receptor antagonist, per the FDA's Established Pharmacologic Class.
Is Astepro FDA-registered?
Astepro is on record with the U.S. FDA under application number NDA022203. You can verify this on its official FDA label.
Has Astepro been recalled by the FDA?
Astepro has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Astepro safe?
There's no single safe-or-not verdict. pharmaranks gives Astepro a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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