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alprazolam

Pharmaranks rates Alprazolam 3.3/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Alprazolam is a benzodiazepine used to treat Agoraphobia, Depressive Disorder, Panic Disorder.

Benzodiazepine · by Apotex

Generic of Xanax

66/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Alprazolam
Drug class
Benzodiazepine
Form
Solution, Tablet, Tablet, extended release, Tablet, orally disintegrating
Strength
Alprazolam 0.25MG · Alprazolam 0.5MG · Alprazolam 1MG · Alprazolam 2MG
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Apotex
Half-life
about 11 hours (mean 11.2 hours; range roughly 6 to 27 hours) in healthy adults (how long it stays in your system)
What the pharmacy pays
~$0.76 for 30 — not your price
FDA application
ANDA077741
Availability
Discontinued (per FDA)

How long does Alprazolam stay in your body?

The elimination half-life of alprazolam is about 11 hours (mean 11.2 hours; range roughly 6 to 27 hours) in healthy adults — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The elimination half-life runs longer in older adults (mean about 16 hours) and in people with liver disease or obesity (means around 20 to 22 hours), so it varies widely by population; alprazolam's minor active metabolites are present at very low levels (under 4% of the parent) with lower potency and do not meaningfully extend its effect.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: ALPRAZOLAM tablet — DailyMed (NIH).

Drug class

How this class works, per Benzodiazepines — StatPearls, NCBI Bookshelf (NIH).

May treat (source: NIH RxClass)

See how Alprazolam ranks — best-rated benzodiazepine for:

Dosage forms

Solution, Tablet, Tablet, extended release and Tablet, orally disintegrating

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Alprazolam treat?
Alprazolam (Alprazolam) may be used to treat agoraphobia, depressive disorder, panic disorder, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Alprazolam work?
Alprazolam is a benzodiazepine. Benzodiazepines boost the brain's main calming chemical, GABA, by binding to the GABA-A receptor and making its chloride channel open more often. This quiets nerve activity, producing sedation, reduced anxiety, muscle relaxation, and protection against seizures.
How is Alprazolam rated?
pharmaranks gives Alprazolam a composite score of 3.3 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Alprazolam cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.76 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Alprazolam?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Alprazolam. To pay less, Alprazolam is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Alprazolam?
Alprazolam is marketed by Apotex. You can see Apotex's full profile, rating, and other products on pharmaranks.
Is Alprazolam a brand-name or generic drug?
Alprazolam is a generic medication; its active ingredient is Alprazolam. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Alprazolam available over the counter?
No. Alprazolam is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Alprazolam come in?
Alprazolam is currently marketed as solution, tablet, tablet, extended release and tablet, orally disintegrating, per the FDA's National Drug Code Directory.
What class of drug is Alprazolam?
Alprazolam is classified as benzodiazepine, per the FDA's Established Pharmacologic Class.
Is Alprazolam FDA-registered?
Alprazolam is on record with the U.S. FDA under application number ANDA077741. You can verify this on its official FDA label.
Has Alprazolam been recalled by the FDA?
Alprazolam has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Alprazolam safe?
There's no single safe-or-not verdict. pharmaranks gives Alprazolam a recall-safety score of 66/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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alprazolam

66/100