ALPRAZOLAM vs TEMAZEPAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. ALPRAZOLAM and TEMAZEPAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ALPRAZOLAM	TEMAZEPAM
Rating	66/100	72/100
Pharmacy pays	~$0.76 /30	~$2.73 /30
Type	RX	RX
Active ingredient	ALPRAZOLAM	TEMAZEPAM
Manufacturer	Apotex	Prinston Inc
Dosage forms	Solution, Tablet, Tablet, extended release, Tablet, orally disintegrating	Capsule
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	None	Boxed warning
Half-life	about 11 hours (mean 11.2 hours; range roughly 6 to 27 hours) in healthy adults	—
Treats	Agoraphobia, Depressive Disorder, Panic Disorder	Depressive Disorder, Sleep Initiation and Maintenance Disorders, Panic Disorder

alprazolam temazepam

Rating

66/100

72/100

Pharmacy pays

~$0.76 /30

~$2.73 /30

Type

Active ingredient

ALPRAZOLAM

TEMAZEPAM

Manufacturer

Apotex

Prinston Inc

Dosage forms

Solution, Tablet, Tablet, extended release, Tablet, orally disintegrating

Capsule

Drug class

Benzodiazepine

Boxed warning

None

Boxed warning

Half-life

about 11 hours (mean 11.2 hours; range roughly 6 to 27 hours) in healthy adults

—

Treats

Agoraphobia, Depressive Disorder, Panic Disorder

Depressive Disorder, Sleep Initiation and Maintenance Disorders, Panic Disorder

Frequently asked questions

Which is better-rated, Alprazolam or Temazepam?

By our independent rating, Temazepam scores higher — 3.6 vs 3.3 out of 5 for Alprazolam. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Alprazolam or Temazepam?

Alprazolam costs pharmacies less to acquire — about $0.76 vs $2.73 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Alprazolam and Temazepam?

Alprazolam contains Alprazolam, while Temazepam contains Temazepam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.